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FTO gene

Known as: FTO, KIAA1752, fat mass and obesity associated 
This gene is involved in the demethylation of nucleic acids.
National Institutes of Health

Related topics

Related topics

7 relations
Alpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanIron ChelationNucleotide Metabolism

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FTO wt Allele

Papers overview

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Highly Cited
2015
Highly Cited
2015
FTO influences adipogenesis by regulating mitotic clonal expansion
The fat mass and obesity-associated (FTO) gene plays a pivotal role in regulating body weight and fat mass; however, the… 
Highly Cited
2015
Highly Cited
2015
Decreased N(6)-methyladenosine in peripheral blood RNA from diabetic patients is associated with FTO expression rather than ALKBH5.
CONTEXT N(6)-methyladenosine (m(6)A) modification plays a fundamental role in the epigenetic regulation of the mammalian… 
Highly Cited
2013
Highly Cited
2013
Role for the obesity-related FTO gene in the cellular sensing of amino acids
SNPs in the first intron of FTO (fat mass and obesity associated) are strongly associated with human obesity. While it is not yet… 
Highly Cited
2011
Highly Cited
2011
The role of the fat mass and obesity associated gene (FTO) in breast cancer risk
BackgroundObesity has been shown to increase breast cancer risk. FTO is a novel gene which has been identified through genome… 
Highly Cited
2011
Highly Cited
2011
Rutile TiO2 nano-branched arrays on FTO for dye-sensitized solar cells.
Hierarchical TiO(2) nanostructures would be desirable for preparing dye-sensitized solar cells because of their large amount of… 
Highly Cited
2010
Highly Cited
2010
The Fat Mass and Obesity Associated Gene FTO Functions in the Brain to Regulate Postnatal Growth in Mice
FTO (fat mass and obesity associated) was identified as an obesity-susceptibility gene by several independent large-scale genome… 
Highly Cited
2009
Highly Cited
2009
Combined effects of MC4R and FTO common genetic variants on obesity in European general populations
Genome-wide association scans recently identified common polymorphisms, in intron 1 of FTO and 188 kb downstream MC4R, that… 
Highly Cited
2009
Highly Cited
2009
Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue
OBJECTIVE Common variants in FTO (the fat mass– and obesity-associated gene) associate with obesity and type 2 diabetes. The… 
Highly Cited
2008
Highly Cited
2008
Physical activity and the association of common FTO gene variants with body mass index and obesity.
BACKGROUND Common FTO (fat mass and obesity associated) gene variants have recently been associated with body mass index (BMI… 
Highly Cited
2008
Highly Cited
2008
Exploring the Developmental Overnutrition Hypothesis Using Parental–Offspring Associations and FTO as an Instrumental Variable
Background The developmental overnutrition hypothesis suggests that greater maternal obesity during pregnancy results in… 
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