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DNA, Mitochondrial

Known as: DNA, Mitochondrial [Chemical/Ingredient], mtDNA, Mitochondrial DNA 
Typically small, circular, intronless, and maternally inherited, mitochondrial DNA (mtDNA) is the multicopy deoxyribonucleic acid genome of… Expand
National Institutes of Health

Related topics

Related topics

30 relations

Narrower (1)

COXIII protein, Oryza sativa
Clinical Data Interchange Standards Consortium TerminologyExtrachromosomal InheritanceGenes, MitochondrialIn Blood
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Broader (3)

DNAMitochondrial matrixextrachromosomal DNA

Papers overview

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Highly Cited
2005
Highly Cited
2005
Dating of the human-ape splitting by a molecular clock of mitochondrial DNA
SummaryA new statistical method for estimating divergence dates of species from DNA sequence data by a molecular clock approach… Expand
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Highly Cited
2005
Highly Cited
2005
Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging
Mutations in mitochondrial DNA (mtDNA) accumulate in tissues of mammalian species and have been hypothesized to contribute to… Expand
Highly Cited
2004
Highly Cited
2004
Premature ageing in mice expressing defective mitochondrial DNA polymerase
Point mutations and deletions of mitochondrial DNA (mtDNA) accumulate in a variety of tissues during ageing in humans, monkeys… Expand
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Review
1999
Review
1999
Animal mitochondrial genomes.
  • J. Boore
  • Nucleic acids research
  • 1999
    • Corpus ID: 17907072
Animal mitochondrial DNA is a small, extrachromosomal genome, typically approximately 16 kb in size. With few exceptions, all… Expand
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Highly Cited
1997
Highly Cited
1997
Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress.
A significant amount of reactive oxygen species (ROS) is generated during mitochondrial oxidative phosphorylation. Several… Expand
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Highly Cited
1993
Highly Cited
1993
Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees.
Examining the pattern of nucleotide substitution for the control region of mitochondrial DNA (mtDNA) in humans and chimpanzees… Expand
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Highly Cited
1989
Highly Cited
1989
Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.
With a standard set of primers directed toward conserved regions, we have used the polymerase chain reaction to amplify… Expand
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Highly Cited
1988
Highly Cited
1988
Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
In vitro studies of muscle mitochondrial metabolism in patients with mitochondrial myopathy have identified a variety of… Expand
Highly Cited
1988
Highly Cited
1988
Normal oxidative damage to mitochondrial and nuclear DNA is extensive.
Oxidative damage to DNA can be caused by excited oxygen species, which are produced by radiation or are by-products of aerobic… Expand
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Highly Cited
1987
Highly Cited
1987
Rates of nucleotide substitution vary greatly among plant mitochondrial, chloroplast, and nuclear DNAs.
Comparison of plant mitochondrial (mt), chloroplast (cp) and nuclear (n) DNA sequences shows that the silent substitution rate in… Expand
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