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DNA, Mitochondrial
Known as:
DNA, Mitochondrial [Chemical/Ingredient]
, mtDNA
, Mitochondrial DNA
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Typically small, circular, intronless, and maternally inherited, mitochondrial DNA (mtDNA) is the multicopy deoxyribonucleic acid genome of…
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National Institutes of Health
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Related topics
Related topics
30 relations
Narrower (1)
COXIII protein, Oryza sativa
Clinical Data Interchange Standards Consortium Terminology
Extrachromosomal Inheritance
Genes, Mitochondrial
In Blood
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Broader (3)
DNA
Mitochondrial matrix
extrachromosomal DNA
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
K. Nakahira
,
J. Haspel
,
+10 authors
A. Choi
Nature Immunology
2011
Corpus ID: 195684393
Autophagy, a cellular process for organelle and protein turnover, regulates innate immune responses. Here we demonstrate that…
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Highly Cited
2005
Highly Cited
2005
Dating of the human-ape splitting by a molecular clock of mitochondrial DNA
M. Hasegawa
,
H. Kishino
,
T. Yano
Journal of Molecular Evolution
2005
Corpus ID: 25554168
SummaryA new statistical method for estimating divergence dates of species from DNA sequence data by a molecular clock approach…
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Highly Cited
2005
Highly Cited
2005
Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging
G. Kujoth
,
A. Hiona
,
+15 authors
T. Prolla
Science
2005
Corpus ID: 23993160
Mutations in mitochondrial DNA (mtDNA) accumulate in tissues of mammalian species and have been hypothesized to contribute to…
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Highly Cited
2004
Highly Cited
2004
Premature ageing in mice expressing defective mitochondrial DNA polymerase
A. Trifunovic
,
A. Wredenberg
,
+10 authors
N. Larsson
Nature
2004
Corpus ID: 4327793
Point mutations and deletions of mitochondrial DNA (mtDNA) accumulate in a variety of tissues during ageing in humans, monkeys…
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Review
1999
Review
1999
Animal mitochondrial genomes.
J. Boore
Nucleic Acids Research
1999
Corpus ID: 17907072
Animal mitochondrial DNA is a small, extrachromosomal genome, typically approximately 16 kb in size. With few exceptions, all…
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Highly Cited
1997
Highly Cited
1997
Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress.
F. Yakes
,
B. V. Houten
Proceedings of the National Academy of Sciences…
1997
Corpus ID: 22998735
A significant amount of reactive oxygen species (ROS) is generated during mitochondrial oxidative phosphorylation. Several…
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Highly Cited
1993
Highly Cited
1993
Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees.
Kazuko Tamura
,
M. Nei
Molecular biology and evolution
1993
Corpus ID: 13857947
Examining the pattern of nucleotide substitution for the control region of mitochondrial DNA (mtDNA) in humans and chimpanzees…
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Highly Cited
1989
Highly Cited
1989
Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.
T. Kocher
,
W. Thomas
,
+4 authors
A. Wilson
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 13226887
With a standard set of primers directed toward conserved regions, we have used the polymerase chain reaction to amplify…
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Highly Cited
1988
Highly Cited
1988
Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
I. Holt
,
A. Harding
,
J. Morgan-Hughes
Nature
1988
Corpus ID: 4248634
In vitro studies of muscle mitochondrial metabolism in patients with mitochondrial myopathy have identified a variety of…
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Highly Cited
1987
Highly Cited
1987
Rates of nucleotide substitution vary greatly among plant mitochondrial, chloroplast, and nuclear DNAs.
K. H. Wolfe
,
Wen-Hsiung Li
,
P. Sharp
Proceedings of the National Academy of Sciences…
1987
Corpus ID: 2836269
Comparison of plant mitochondrial (mt), chloroplast (cp) and nuclear (n) DNA sequences shows that the silent substitution rate in…
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