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Genetic Evidence for an East Asian Origin of Domestic Dogs
A larger genetic variation in East Asia than in other regions and the pattern of phylogeographic variation suggest an East Asian origin for the domestic dog, ∼15,000 years ago. Expand
Phylogeographic differentiation of mitochondrial DNA in Han Chinese.
These and other features of the geographical distribution of the mtDNA haplogroups observed in the Han Chinese make an initial Paleolithic colonization from south to north plausible but would suggest subsequent migration events in China that mainly proceeded from north to south and east to west. Expand
Multiple maternal origins of chickens: out of the Asian jungles.
Different clades may originate from different regions, such as Yunnan, South and Southwest China and/or surrounding areas (i.e., Vietnam, Burma, and Thailand), and the Indian subcontinent, which support the theory of multiple origins in South and Southeast Asia. Expand
Evidence of positive selection acting at the human dopamine receptor D4 gene locus
  • Y. Ding, H. Chi, +9 authors R. Moyzis
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 26 December 2001
It is shown by DNA resequencing/haplotyping of 600 DRD4 alleles, representing a worldwide population sample, that the origin of 2R–6R alleles can be explained by simple one-step recombination/mutation events and the 7R allele originated as a rare mutational event that nevertheless increased to high frequency in human populations by positive selection. Expand
Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication
It is shown that dog breeds share a higher proportion of multi-locus haplotypes unique to grey wolves from the Middle East, indicating that they are a dominant source of genetic diversity for dogs rather than wolves from east Asia, as suggested by mitochondrial DNA sequence data. Expand
Updating the East Asian mtDNA phylogeny: a prerequisite for the identification of pathogenic mutations.
A reassessment of the mtDNA data from a series of disease studies testified to the usefulness of such a refined mtDNA tree in evaluating the pathogenicity of mtDNA mutations and a guideline based on the phylogenetic knowledge as proposed here could help avoiding similar problems in the future. Expand
The sequence and de novo assembly of the giant panda genome
This corrects the article to show that the Higgs boson genome is a “spatially aggregating ‘spatiotemporal ’ organisation’, rather than a ‘cell-based’ organisation, which is more closely related to the immune system. Expand
Genetic relationship of Chinese ethnic populations revealed by mtDNA sequence diversity.
Phylogenetic analysis and haplotype sharing among populations suggest that current mtDNA variation in these ethnic populations could reveal their ethnohistory to some extent, but in general, linguistic and geographic classifications of the populations did not agree well with classification by mt DNA variation. Expand
Different matrilineal contributions to genetic structure of ethnic groups in the silk road region in china.
Direct evidence supporting the suggestion that Central Asia is the location of genetic admixture of the East and the West is provided, with the highest frequency present in Uygur and Uzbek samples, and no western Eurasian type was found in Han Chinese samples from the same place. Expand
Phylogeny of mitochondrial DNA macrohaplogroup N in India, based on complete sequencing: implications for the peopling of South Asia.
It is demonstrated that the Indian mt DNA pool, even when restricted to macrohaplogroup N, harbors at least as many deepest-branching lineages as the western Eurasian mtDNA pool. Expand