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DLC1 gene

Known as: RHO GTPase-ACTIVATING PROTEIN 7, HP, p122-RhoGAP 
This gene plays a role in cytoskeletal organization and regulation of cell growth.
National Institutes of Health

Related topics

Related topics

6 relations
Cell Growth RegulationCytoskeletal ModelingDLC1 protein, humanSignal Transduction

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DLC1 wt AlleleDLEC1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Regulation of deleted in liver cancer 1 tumor suppressor by protein–protein interactions and phosphorylation
The deleted in liver cancer 1 (DLC1) tumor suppressor is an important RhoGTP activating protein (RhoGAP) that plays a crucial… 
2012
2012
Loss of DLC1 is an independent prognostic factor in patients with oral squamous cell carcinoma
Deleted in liver cancer (DLC1), a Rho GTPase-activating protein, was observed to be differentially expressed in oral squamous… 
2011
2011
Silencing of DLC1 Upregulates PAI-1 Expression and Reduces Migration in Normal Prostate Cells
Deleted in liver cancer 1 (DLC1) is a GTPase-activating protein (GAP) domain containing tumor suppressor that localizes to focal… 
2011
2011
Detection and clinical significance of DLC1 gene methylation in serum DNA from colorectal cancer patients
ObjectiveDeleted in liver cancer 1 (DLC1) is a new candidate tumor suppressor gene, whose down-regulation or even silence will… 
2009
2009
Overexpression of DLC-1 induces cell apoptosis and proliferation inhibition in the renal cell carcinoma.
2009
2009
Restoration of DLC1 gene inhibits proliferation and migration of human colon cancer HT29 cells.
DLC1 (deleted in liver cancer-1) is a new candidate tumor suppressor gene, which is inactive in various types of human cancers… 
2008
2008
IDENTIFICATION OF THE DELETED IN LIVER CANCER 1 GENE, DLC1, AS A CANDIDATE MENINGIOMA TUMOR SUPPRESSOR
OBJECTIVEMeningiomas are the second most common primary tumors of the central nervous system. Meningiomas at the cranial base… 
2008
2008
Inhibition of DLC-1 gene expression by RNA interference in the colon cancer LoVo cell line.
DLC-1 (deleted in liver cancer-1) is a potential tumor suppressor gene, which is inactive in liver carcinogenesis. To observe the… 
2005
2005
Epigenetic inactivation of DLC-1 in supratentorial primitive neuroectodermal tumor.
2002
2002
Gene structure, tissue expression, and linkage mapping of the mouse DLC-1 gene (Arhgap7).
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