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DLC1 protein, human

Known as: Rho GTPase-Activating Protein 7, Deleted in Liver Cancer 1 Protein, START Domain-Containing Protein 12 
Rho GTPase-activating protein 7 (1528 aa, ~171 kDa) is encoded by the human DLC1 gene. This protein is involved in the mediation of both signal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The DLC1 gene encodes a Rho GTPase-activating protein (RhoGAP) that functions as a tumor suppressor in several common human… Expand
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Highly Cited
2008
Highly Cited
2008
Expression of the tumor suppressor deleted in liver cancer-1 (DLC-1) is lost in non-small cell lung (NSCLC) and other human… Expand
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Highly Cited
2007
Highly Cited
2007
Identification of tumor suppressor genes (TSG) silenced by methylation uncovers mechanisms of tumorigenesis and identifies new… Expand
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Highly Cited
2006
Highly Cited
2006
Purpose: The deleted in liver cancer-1 (DLC-1) gene that encodes a Rho GTPase-activating protein with tumor suppressor function… Expand
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Highly Cited
2005
Highly Cited
2005
The identification of molecular signatures characteristic of tumor cells that are capable of metastatic spread is required for… Expand
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Highly Cited
2005
Highly Cited
2005
Although progesterone (P4) has been implicated to offer protection against ovarian cancer (OCa), little is known of its mechanism… Expand
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Highly Cited
2004
Highly Cited
2004
The deleted in liver cancer (DLC-1) gene at chromosome 8p21–22 is altered mainly by genomic deletion or aberrant promoter… Expand
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Highly Cited
2004
Highly Cited
2004
The gene deleted in liver cancer-1 (DLC-1) is located on human chromosome 8p21–22, a region thought to harbor tumor suppressor… Expand
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Highly Cited
2003
Highly Cited
2003
The human DLC-1 (deleted in liver cancer 1) gene was cloned from a primary human hepatocellular carcinoma (HCC) and mapped to the… Expand
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Highly Cited
2000
Highly Cited
2000
We investigated the expression and deletion of DLC-1 (frequently deleted in liver cancer gene), first reported in 1998 and having… Expand
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