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DICER1 protein, human

Known as: Endoribonuclease Dicer, Helicase with RNase Motif, K12H4.8-Like 
Endoribonuclease Dicer (1922 aa, ~219 kDa) is encoded by the human DICER1 gene. This protein plays a role in both pri-miRNA processing and RNA… 
National Institutes of Health

Related topics

Related topics

17 relations
Cell NucleusDICER1 geneDICER1 wt AlleleDouble-Stranded RNA Binding Motif

Broader (2)

DEAD-box RNA HelicasesRibonuclease III

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Dicer ablation in osteoblasts by Runx2 driven cre-loxP recombination affects bone integrity, but not glucocorticoid-induced suppression of bone formation
Glucocorticoid-induced osteoporosis (GIO) is one of the major side effects of long-term glucocorticoid (GC) therapy mediated… 
Highly Cited
2013
Highly Cited
2013
DICER1, DROSHA and miRNAs in patients with non-small cell lung cancer: implications for outcomes and histologic classification.
The clinical and functional significance of RNA-interference machinery in lung cancer is poorly understood. Besides, microRNAs… 
2013
2013
Repression of Dicer is associated with invasive phenotype and chemoresistance in ovarian cancer
Dicer is a key enzyme that processes microRNA (miRNA) precursors into their mature form, enabling them to regulate gene… 
2012
2012
Genetic Variations in Key MicroRNA Processing Genes and Risk of Head and Neck Cancer: A Case-Control Study in Chinese Population
MicroRNAs (miRNAs) have been reported to play a key role in oncogenesis. Genetic variations in miRNA processing genes and miRNA… 
2012
2012
Methods for validation of miRNA sequence variants and the cleavage of their targets.
Highly Cited
2010
Highly Cited
2010
RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells
An important function of the RNAase-III enzyme Dicer is to process microRNA precursors into ~22-nucleotide non-coding small RNAs… 
Highly Cited
2009
Highly Cited
2009
Non-cell-autonomous effects of vector-expressed regulatory RNAs in mammalian heart cells
In mammalian cells, small regulatory RNA molecules are able to modulate gene expression in a cell-autonomous manner. In contrast… 
2007
2007
Dissection of Double-Stranded RNA Binding Protein B2 from Betanodavirus
ABSTRACT Betanodaviruses are small RNA viruses that infect teleost fish and pose a considerable threat to marine aquaculture… 
2007
2007
Decreased expression of DICER1 in gastric cancer.
BACKGROUND The role of epigenetics in gene expression regulation and development significantly enhances our understanding of… 
2006
2006
Blueprint of an oil-eating bacterium
The genome sequence of a bacterium that degrades marine hydrocarbons should facilitate bioremediation efforts. 
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