Skip to search formSkip to main contentSkip to account menu

Double-Stranded RNA Binding Motif

Known as: Double Stranded RNA Binding Domain, Double-Stranded RNA Binding Domain, dsRBM 
The Double-Stranded RNA Binding Domain is found in a variety of RNA-binding proteins with different structures and exhibiting a diversity of… 
National Institutes of Health

Related topics

Related topics

8 relations
40S Ribosoma Protein S2DICER1 protein, humanEIF2AK2 protein, humanMicroprocessor Complex Subunit DGCR8

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells.
Drosha is a key enzyme in microRNA biogenesis, generating the precursor miRNA (pre-miRNA) by excising the stem-loop embedded in… 
Highly Cited
2011
Highly Cited
2011
Structure of a yeast RNase III dsRBD complex with a noncanonical RNA substrate provides new insights into binding specificity of dsRBDs.
2011
2011
A Drosophila genetic screen yields allelic series of core microRNA biogenesis factors and reveals post-developmental roles for microRNAs.
Canonical animal microRNAs (miRNAs) are ∼22-nt regulatory RNAs generated by stepwise cleavage of primary hairpin transcripts by… 
2010
2010
Dynamic origins of differential RNA binding function in two dsRBDs from the miRNA "microprocessor" complex.
MicroRNAs (miRNAs) affect gene regulation by base pairing with mRNA and contribute to the control of cellular homeostasis. The… 
2010
2010
Solution structure of the Drosha double-stranded RNA-binding domain
BackgroundDrosha is a nuclear RNase III enzyme that initiates processing of regulatory microRNA. Together with partner protein… 
2004
2004
A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III.
Rnt1 endoribonuclease, the yeast homolog of RNAse III, plays an important role in the maturation of a diverse set of RNAs. The… 
Review
2003
Review
2003
Recognition of double-stranded RNA by proteins and small molecules.
Molecular recognition of double-stranded RNA (dsRNA) is a key event for numerous biological pathways including the trafficking… 
Highly Cited
2000
Highly Cited
2000
Substrate recognition by a eukaryotic RNase III: the double-stranded RNA-binding domain of Rnt1p selectively binds RNA containing a 5'-AGNN-3' tetraloop.
Rnt1p is an RNase III homolog from budding yeast, required for processing snRNAs, snoRNAs, and rRNA. Numerous Rnt1p RNA… 
Highly Cited
2000
Highly Cited
2000
The N-Terminal Domain That Distinguishes Yeast from Bacterial RNase III Contains a Dimerization Signal Required for Efficient Double-Stranded RNA Cleavage
ABSTRACT Yeast Rnt1 is a member of the double-stranded RNA (dsRNA)-specific RNase III family identified by conserved dsRNA… 
1998
1998
An Arg/Lys-rich core peptide mimics TRBP binding to the HIV-1 TAR RNA upper-stem/loop.
TRBP is a cellular protein that binds to the HIV-1 leader RNA, TAR. Circular dichroism experiments have shown that a 24 amino… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)