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DICER1 wt Allele

Known as: DCR-1 Homolog Gene, HERNA, DICER 
Human DICER1 wild-type allele is located in the vicinity of 14q32.13 and is approximately 71 kb in length. This allele, which encodes… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Aberrant expression of microRNAs (miRNAs) and the enzymes that control their processing have been reported in multiple biological… Expand
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Highly Cited
2010
Highly Cited
2010
Competition between mammalian RNAi-related gene silencing pathways is well documented. It is therefore important to identify all… Expand
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Highly Cited
2008
Highly Cited
2008
To explore the role of Dicer-dependent control mechanisms in B lymphocyte development, we ablated this enzyme in early B cell… Expand
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Highly Cited
2008
Highly Cited
2008
Loss of microRNA (miRNA) pathway components negatively affects differentiation of embryonic stem (ES) cells, but the underlying… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND We studied Dicer and Drosha, components of the RNA-interference machinery, in ovarian cancer. METHODS We measured… Expand
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Highly Cited
2008
Highly Cited
2008
Background MicroRNAs (miRNAs) are critical regulators of transcriptional and post-transcriptional gene silencing, which are… Expand
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Highly Cited
2005
Highly Cited
2005
Dicer is an RNase III-family nuclease that initiates RNA interference (RNAi) and related phenomena by generation of the small… Expand
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Highly Cited
2005
Highly Cited
2005
Emerging evidence suggests that microRNA, which are well‐conserved, abundant and small regulatory RNA, may be involved in the… Expand
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Highly Cited
2005
Highly Cited
2005
The ribonuclease III enzyme Dicer is essential for the processing of micro-RNAs (miRNAs) and small interfering RNAs (siRNAs) from… Expand
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Highly Cited
2003
Highly Cited
2003
A number of genes have been identified as members of the Argonaute family in various nonhuman organisms and these genes are… Expand
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