DICER1 wt Allele

Known as: DCR-1 Homolog Gene, HERNA, DICER 
Human DICER1 wild-type allele is located in the vicinity of 14q32.13 and is approximately 71 kb in length. This allele, which encodes… (More)
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Short hairpin RNA (shRNA)-induced RNAi is used for biological discovery and therapeutics. Dicer, whose normal role is to liberate… (More)
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Highly Cited
2010
Highly Cited
2010
Competition between mammalian RNAi-related gene silencing pathways is well documented. It is therefore important to identify all… (More)
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Highly Cited
2008
Highly Cited
2008
Loss of microRNA (miRNA) pathway components negatively affects differentiation of embryonic stem (ES) cells, but the underlying… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND We studied Dicer and Drosha, components of the RNA-interference machinery, in ovarian cancer. METHODS We measured… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND MicroRNAs (miRNAs) are critical regulators of transcriptional and post-transcriptional gene silencing, which are… (More)
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Highly Cited
2008
Highly Cited
2008
MicroRNAs (miRNAs) are small noncoding RNAs that can act to repress target mRNAs by suppressing translation and/or reducing mRNA… (More)
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Highly Cited
2007
Highly Cited
2007
Short RNA expression was analyzed from Dicer-positive and Dicer-knockout mouse embryonic [corrected] stem (ES) cells, using high… (More)
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Highly Cited
2005
Highly Cited
2005
Emerging evidence suggests that microRNA, which are well-conserved, abundant and small regulatory RNA, may be involved in the… (More)
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Highly Cited
2003
Highly Cited
2003
A number of genes have been identified as members of the Argonaute family in various nonhuman organisms and these genes are… (More)
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Highly Cited
2002
Highly Cited
2002
Mutations in the Arabidopsis ROS1 locus cause transcriptional silencing of a transgene and a homologous endogenous gene. In the… (More)
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