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DAXX gene

Known as: death-domain associated protein, DAXX, DEATH-ASSOCIATED PROTEIN 6 
This gene plays a role in signal transduction, regulation of transcription and enhancement of apoptosis.
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Glioblastoma multiforme (GBM) is a lethal brain tumour in adults and children. However, DNA copy number and gene expression… Expand
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Highly Cited
2012
Highly Cited
2012
Poorly differentiated neuroendocrine carcinomas (NECs) of the pancreas are rare malignant neoplasms with a poor prognosis. The… Expand
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Highly Cited
2011
Highly Cited
2011
A rare but deadly form of human pancreatic cancer harbors mutations in chromatin remodeling genes. Pancreatic neuroendocrine… Expand
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Highly Cited
2008
Highly Cited
2008
The apoptosis-modulating protein Daxx functions as a transcriptional repressor that binds to and suppresses the activity of… Expand
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Highly Cited
2004
Highly Cited
2004
Placing regulatory proteins into different multiprotein complexes should modify key cellular processes. Here, we show that the… Expand
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Highly Cited
2002
Highly Cited
2002
Daxx has been reported to mediate the Fas/JNK-dependent signals in the cytoplasm. However, several lines of evidence have… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT Heat shock protein 27 (HSP27) confers cellular protection against a variety of cytotoxic stresses and also against… Expand
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Highly Cited
2000
Highly Cited
2000
The promyelocytic leukemia protein (PML) gene of acute promyelocytic leukemia (APL) encodes a cell growth and tumor suppressor… Expand
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Highly Cited
1999
Highly Cited
1999
The mammalian Daxx gene has been identified in a diverse set of yeast interaction trap experiments. Although a facilitating role… Expand
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Highly Cited
1997
Highly Cited
1997
The Fas cell surface receptor induces apoptosis upon receptor oligomerization. We have identified a novel signaling protein… Expand
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