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D-600

Known as: 600 d, D 600, D600 
National Institutes of Health

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1 relation

Broader (1)

Gallopamil

Papers overview

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Highly Cited
1999
Highly Cited
1999
Bepridil differentially inhibits two delayed rectifier K+ currents, IKr and IKs, in guinea‐pig ventricular myocytes
We investigated the effects of bepridil on the two components of the delayed rectifier K+ current, i.e., the rapidly activating… 
Highly Cited
1992
Highly Cited
1992
Synchronized Repolarization After Defibrillation Shocks: A Possible Component of the Defibrillation Process Demonstrated by Optical Recordings in Rabbit Heart
BackgroundIt is currently believed that defibrillation shocks act primarily by stimulating excitable myocardium to abolish wave… 
Highly Cited
1989
Highly Cited
1989
Changes in intracellular free calcium in isolated myometrial cells: role of extracellular and intracellular calcium and possible involvement of guanine nucleotide-sensitive proteins.
Intracellular free calcium concentrations were measured directly in rat myometrial cells loaded with fura-2. The basal… 
Highly Cited
1988
Highly Cited
1988
Voltage dependence of sodium‐calcium exchange current in guinea‐pig atrial myocytes determined by means of an inhibitor.
1. Spontaneous transient inward currents (Iti) caused by cyclic release of Ca2+ ions from the sarcoplasmic reticulum were studied… 
Highly Cited
1985
Highly Cited
1985
Calcium channel antagonists inhibit the acrosome reaction and bind to plasma membranes of sea urchin sperm.
As a prerequisite to fertilization, sea urchin sperm undergo an acrosome reaction that is mediated in part by increased… 
Highly Cited
1984
Highly Cited
1984
Modulation of phospholipase A2 activity associated with human sperm membranes by divalent cations and calcium antagonists.
Phospholipase A2 activity in sonicates and acid extracts of ejaculated, washed human sperm was measured using [1-14C] oleate… 
Highly Cited
1984
Highly Cited
1984
Differentiation of receptor sites for [3H]nitrendipine in chick hearts and physiological relation to the slow Ca2+ channel and to excitation-contraction coupling.
The properties of interaction of the Ca2+ channel antagonist [3H]nitrendipine have been investigated in chick hearts at various… 
Highly Cited
1984
Highly Cited
1984
Charge movement in skeletal muscle fibers paralyzed by the calcium-entry blocker D600.
We report measurements of nonlinear charge movement in frog skeletal muscle fibers paralyzed by the calcium-entry blocker… 
Highly Cited
1982
Highly Cited
1982
ELECTRICAL SLOW WAVES AND TONE OF GUINEA‐PIG ISOLATED TRACHEALIS MUSCLE: EFFECTS OF DRUGS AND TEMPERATURE CHANGES
1 Simultaneous recordings of electrical and mechanical activity have been made from guinea‐pig isolated trachealis muscle… 
Highly Cited
1980
Highly Cited
1980
The mechanism of alpha-adrenergic activation of the dog coronary artery.
Norepinephrine (NE) activates isolated coronary conduit arteries by stimulating Ca2+ uptake into the smooth muscle cells… 
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