Cyclosporins

Known as: Cyclosporine, Cyclosporines, Cyclosporins [Chemical/Ingredient] 
A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2018
05101519772018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Viruses are obligate intracellular parasites and therefore their replication completely depends on host cell factors. In case of… (More)
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2004
2004
The Cyclosporins A, B, C, D and G are cyclic undecapeptides produced by the fungus Tolypocladium inflatum Gams which vary in the… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Many pharmacologically important peptides are synthesized nonribosomally by multimodular peptide synthetases (NRPSs… (More)
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1997
1997
A variant of the multidrug-resistant human sarcoma cell line Dx5 was derived by co-selection with doxorubicin and the cyclosporin… (More)
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1996
1996
Human immunodeficiency virus type 1 mutants that are resistant to inhibition by cyclosporins arise spontaneously in vitro during… (More)
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1994
1994
The pharmacokinetic dose proportionality and relative bioavailability of cyclosporine from a microemulsion formulation… (More)
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1993
1993
The distinct ATP-dependent transporters for taurocholate, leukotriene C4, and daunorubicin, studied in rat liver canalicular… (More)
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Highly Cited
1991
Highly Cited
1991
The Ki values of cyclosporins A, G and H for the peptidyl-prolyl cis-trans isomerase (PPIase) of liver and heart mitochondria are… (More)
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1990
1990
The mechanism of reversal of resistance to Vinca alkaloids by cyclosporins is unclear. We investigated the molecular mechanism of… (More)
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1989
1989
Cyclosporin A (ciclosporin), a potent and clinically important immunosuppressive drug (Sandimmun), represents the main component… (More)
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