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Cuprizone

Known as: Oxaldihydrazone, Biscyclohexanone, Cuprizone [Chemical/Ingredient], Ethanedioic acid, bis(cyclohexylidenehydrazide) 
Copper chelator that inhibits monoamine oxidase and causes liver and brain damage.
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Chelating AgentsMonoamine Oxidase Inhibitors
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Cuprizone induced-demyelination in mice alters brain expression of genes involved in arachidonic acid metabolism .
regulation of Foxp3 is not understood yet. Because IL-12p40 homodimer (p40-2) is markedly up-regulated in response to various… 
2006
2006
Implications of protease M/neurosin in myelination during experimental demyelination and remyelination
1999
1999
Neocuproine potentiates the activity of the nitrergic neurotransmitter but inhibits that of S-nitrosothiols.
1998
1998
Reaction of peroxynitrite with HEPES or MOPS results in the formation of nitric oxide donors.
1990
1990
Induction of myelin-associated glycoprotein mRNA in experimental remyelination
1983
1983
Kinetics of Lucifer yellow CH efflux in giant mitochondria.
1983
1983
Immunohistochemical demonstration of glial fibrillary acidic protein in scrapie.
1978
1978
Methylamine dehydrogenase of Pseudomonas sp. J. Purification and properties.
1977
1977
Inhibition by pargyline of cardiovascular amine oxidase activity.
Highly Cited
1971
Highly Cited
1971
Histopathological Similarities between Scrapie and Cuprizone Toxicity in Mice
PREVIOUS work with scrapie led us to conclude1 that the transmissible agent was unlikely to be a conventional virus. We have… 
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