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Cuprizone

Known as: Oxaldihydrazone, Biscyclohexanone, Cuprizone [Chemical/Ingredient], Ethanedioic acid, bis(cyclohexylidenehydrazide) 
Copper chelator that inhibits monoamine oxidase and causes liver and brain damage.
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Chelating AgentsMonoamine Oxidase Inhibitors
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Short-Term Cuprizone Feeding Verifies N-Acetylaspartate Quantification as a Marker of Neurodegeneration
Proton magnetic resonance spectroscopy (1H-MRS) is a quantitative MR imaging technique often used to complement conventional MR… 
2001
2001
Role of copper ions and cytochrome P450 in the vasodilator actions of the nitroxyl anion generator, Angeli's salt, on rat aorta.
1999
1999
Neocuproine potentiates the activity of the nitrergic neurotransmitter but inhibits that of S-nitrosothiols.
1993
1993
Atypical localization of the oligodendrocytic isoform (PI) of glutathione‐S‐transferase in astrocytes during cuprizone intoxication
Immunocytochemical staining for the Pi and Mu isoforms of glutathione‐S‐transferase was used to investigate changes in the glial… 
1990
1990
Induction of myelin-associated glycoprotein mRNA in experimental remyelination
1983
1983
Kinetics of Lucifer yellow CH efflux in giant mitochondria.
1978
1978
Methylamine dehydrogenase of Pseudomonas sp. J. Purification and properties.
1978
1978
Histopathological and enzyme histochemical changes in experimental Semliki Forest virus infection in mice and their relevance to scrapie.
1977
1977
Inhibition by pargyline of cardiovascular amine oxidase activity.
Highly Cited
1971
Highly Cited
1971
Histopathological Similarities between Scrapie and Cuprizone Toxicity in Mice
PREVIOUS work with scrapie led us to conclude1 that the transmissible agent was unlikely to be a conventional virus. We have… 
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