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Cuprizone

Known as: Oxaldihydrazone, Biscyclohexanone, Cuprizone [Chemical/Ingredient], Ethanedioic acid, bis(cyclohexylidenehydrazide) 
Copper chelator that inhibits monoamine oxidase and causes liver and brain damage.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Abstract Multiple Sclerosis (MS) is a complex disease with an unknown etiology and no effective cure, despite decades of… 
Highly Cited
2012
Highly Cited
2012
Laquinimod (LAQ) is a new oral immunomodulatory compound that reduces relapse rate, brain atrophy and disability progression in… 
Highly Cited
2011
Highly Cited
2011
Vitamin D is emerging as a probably important environmental risk factor in multiple sclerosis, affecting both susceptibility and… 
Highly Cited
2010
Highly Cited
2010
In multiple sclerosis, demyelination occurs beside the white‐matter structures and in the cerebral and cerebellar cortex. We have… 
Highly Cited
2009
Highly Cited
2009
For studies of remyelination in demyelinating diseases, the cuprizone model of CC (corpus callosum) demyelination has… 
Highly Cited
2000
Highly Cited
2000
Metabolic insult results in apoptosis and depletion of mature oligodendrocytes during demyelination. To examine the role of… 
Highly Cited
1979
Highly Cited
1979
Yajima K. & Suzuki K. (1979) Neurobiology and Applied Neuropathology5, 49–62 
Highly Cited
1969
Highly Cited
1969
STATUS SPONGIOSuS has been found in the brain in varioyus neurologic disorders.1 Although, at the light microscopic leveL the…