Cullin Proteins

Known as: Cullin Protein, Cullins, Cullin Domain Proteins 
A family of structurally related proteins that were originally discovered for their role in cell-cycle regulation in CAENORHABDITIS ELEGANS. They… (More)

Topic mentions per year

Topic mentions per year

1999-2017
0246819992017

Papers overview

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2010
2010
The cycle inhibiting factors (Cif), produced by pathogenic bacteria isolated from vertebrates and invertebrates, belong to a… (More)
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Highly Cited
2006
Highly Cited
2006
Cullins assemble the largest family of ubiquitin ligases by binding with ROC1 and various substrate receptors. CUL4 function is… (More)
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Highly Cited
2005
Highly Cited
2005
The concentrations and functions of many eukaryotic proteins are regulated by the ubiquitin pathway, which consists of ubiquitin… (More)
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Highly Cited
2005
Highly Cited
2005
SCF-type E3 ubiquitin ligases are multi-protein complexes required for polyubiquitination and subsequent degradation of target… (More)
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Highly Cited
2004
Highly Cited
2004
Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse… (More)
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Highly Cited
2003
Highly Cited
2003
Cullins (CULs) are subunits of a prominent class of RING ubiquitin ligases. Whereas the subunits and substrates of CUL1… (More)
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Highly Cited
2003
Highly Cited
2003
Programmed destruction of regulatory proteins through the ubiquitin-proteasome system is a widely used mechanism for controlling… (More)
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Highly Cited
2003
Highly Cited
2003
Ubiquitin E3 ligases are a diverse family of protein complexes that mediate the ubiquitination and subsequent proteolytic… (More)
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Highly Cited
2002
Highly Cited
2002
The ubiquitin-like protein, Nedd8, covalently modifies members of the Cullin family. Cullins are the major components of a series… (More)
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Highly Cited
2001
Highly Cited
2001
Although MDM2 plays a major role in regulating the stability of the p53 tumor suppressor protein, other poorly understood MDM2… (More)
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