SKP Cullin F-Box Protein Ligases

Known as: Ubiquitin Ligase, SCF, SKP Cullin F-Box Protein Ligases [Chemical/Ingredient], SCF Ubiquitin Ligase 
A subset of ubiquitin protein ligases that are formed by the association of a SKP DOMAIN PROTEIN, a CULLIN DOMAIN PROTEIN and a F-BOX DOMAIN PROTEIN.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2015
01220052015

Papers overview

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2016
2016
F-box proteins share the F-box domain to connect substrates of E3 SCF ubiquitin RING ligases through the adaptor Skp1/A to Cul1/A… (More)
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Review
2016
Review
2016
87: Theileria buffeli Infections in Grazing Cattle Located in Mountainous Areas of the Republic of Korea Kyoung-Seong Choi*, Joon… (More)
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2015
2015
The Hey protein family, comprising Hey1, Hey2 and HeyL in mammals, conveys Notch signals in many cell types. The helix-loop-helix… (More)
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2015
2015
A GATA family transcription factor GATA binding protein 2 (GATA2) participates in cell growth and differentiation of various… (More)
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Highly Cited
2013
Highly Cited
2013
Skp2 E3 ligase is overexpressed in numerous human cancers and plays a critical role in cell-cycle progression, senescence… (More)
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2011
2011
The human genome encodes 69 different F-box proteins (FBPs), each of which can potentially assemble with Skp1-Cul1-RING to serve… (More)
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2011
2011
The human genome encodes 69 different F-box proteins (FBPs), each of which can potentially assemble with Skp1Cul1-RING to serve… (More)
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Review
2011
Review
2011
The SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex mediates polyubiquitination of proteins targeted for degradation… (More)
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2010
2010
Skeletal muscle is the source of pro- and anti-inflammatory cytokines, and recently, it has been recognized as an important… (More)
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2005
2005
The unique mechanism of the SCF ubiquitin ligase poses a challenge to drug discovery. A central enzymatic small molecule–binding… (More)
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