Cullin 1

Known as: CUL-1, Cullin Homolog 1, Cullin-1 
Cullin-1 (776 aa, ~90 kDa) is encoded by the human CUL1 gene. This protein plays a role in protein ubiquitination and cell cycle regulation.
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Cullin proteins are molecular scaffolds that have crucial roles in the post-translational modification of cellular proteins… (More)
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Highly Cited
2009
Highly Cited
2009
Ubiquitin and ubiquitin-like proteins (UBLs) are directed to targets by cascades of E1, E2, and E3 enzymes. The largest ubiquitin… (More)
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Highly Cited
2007
Highly Cited
2007
The resident prokaryotic microflora of the mammalian intestine influences diverse homeostatic functions of the gut, including… (More)
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Highly Cited
2006
Highly Cited
2006
Dishevelled is a conserved protein that interprets signals received by Frizzled receptors. Using a tandem-affinity purification… (More)
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Highly Cited
2005
Highly Cited
2005
The human enteric flora plays a significant role in intestinal health and disease. Certain enteric bacteria can inhibit the NF… (More)
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Highly Cited
2003
Highly Cited
2003
The concentrations and functions of many cellular proteins are regulated by the ubiquitin pathway. Cullin family proteins bind… (More)
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Highly Cited
2002
Highly Cited
2002
SCF complexes are the largest family of E3 ubiquitin–protein ligases and mediate the ubiquitination of diverse regulatory and… (More)
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Highly Cited
1999
Highly Cited
1999
Recently we found that NEDD8, a ubiquitin-like protein, was linked covalently to human cullin-4A (abbreviated Cul-4A) by a new… (More)
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Highly Cited
1999
Highly Cited
1999
SCFCdc4 (Skp1, Cdc53/cullin, F-box protein) defines a family of modular ubiquitin ligases (E3s) that regulate diverse processes… (More)
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Highly Cited
1996
Highly Cited
1996
The gene cul-1 (formerly lin-19) is a negative regulator of the cell cycle in C. elegans. Null mutations cause hyperplasia of all… (More)
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