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Crigler Najjar syndrome, type 1

Known as: CRIGLER-NAJJAR DISEASE, Crigler-Najjar Syndrome, Type I, Familial Nonhemolytic Unconjugated Hyperbilirubinemia 
A familial form of congenital hyperbilirubinemia transmitted as an autosomal recessive trait. It is characterized by icterus and brain damage caused… 
National Institutes of Health

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Autosomal recessive inheritanceCongenital hyperbilirubinemiaGilbert Disease (disorder)In Blood

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Crigler Najjar syndrome, type 2

Papers overview

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Highly Cited
1999
Highly Cited
1999
Auxiliary partial orthotopic liver transplantation for Crigler-Najjar syndrome type I.
OBJECTIVE To determine if auxiliary partial orthotopic liver transplantation (APOLT) has the long-term potential to correct the… 
Highly Cited
1998
Highly Cited
1998
Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation.
Crigler–Najjar syndrome type I is a recessively inherited disorder characterized by severe unconjugated hyperbilirubinemia… 
Highly Cited
1998
Highly Cited
1998
Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II.
Highly Cited
1997
Highly Cited
1997
Genetic defects of the UDP-glucuronosyltransferase-1 (UGT1) gene that cause familial non-haemolytic unconjugated hyperbilirubinaemias.
Highly Cited
1995
Highly Cited
1995
Analysis of genes for bilirubin UDP-glucuronosyltransferase in Gilbert's syndrome
Highly Cited
1993
Highly Cited
1993
Identification of defect in the genes for bilirubin UDP-glucuronosyl-transferase in a patient with Crigler-Najjar syndrome type II.
Crigler-Najjar syndrome (CN) type II is characterized by severe chronic nonhemolytic unconjugated hyperbilirubinemia due to… 
Highly Cited
1993
Highly Cited
1993
Identification of an A-to-G missense mutation in exon 2 of the UGT1 gene complex that causes Crigler-Najjar syndrome type 2.
Crigler-Najjar syndrome is an inborn error of metabolism that is characterized by severe unconjugated hyperbilirubinemia. The… 
Highly Cited
1993
Highly Cited
1993
Human bilirubin UDP-glucuronosyltransferase catalyzes the glucuronidation of ethinylestradiol.
The synthetic estrogen ethinylestradiol is extensively eliminated as glucuronide metabolites in humans, but the UDP… 
Highly Cited
1992
Highly Cited
1992
Identification of a genetic alteration in the code for bilirubin UDP-glucuronosyltransferase in the UGT1 gene complex of a Crigler-Najjar type I patient.
Patients with Crigler-Najjar syndrome (CN) type I inherit an autosomal recessive trait for hyperbilirubinemia, which is… 
Highly Cited
1992
Highly Cited
1992
Quantitation of transplanted hepatic mass necessary to cure the Gunn rat model of hyperbilirubinemia.
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