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Cortodoxone

Known as: 11-Desoxycortisol, 11-Deoxyhydrocortisone, 11-Desoxycortisone 
17,21-Dihydroxypregn-4-ene-3,20-dione. A 17-hydroxycorticosteroid with glucocorticoid and anti-inflammatory activities.
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (5)

18-hydroxy-11-deoxycortisol21-deoxycortisolTetrahydrodeoxycortisolcortexolone 17alpha-propionate

Broader (6)

Antineoplastic AgentsCorticosteroneDrug CombinationsImmunosuppressive Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Adrenal steroidogenesis in very low birth weight preterm infants.
Adrenal steroidogenesis was evaluated in 25 sick premature infants with a gestational age of less than 30 weeks. ACTH stimulation… 
Highly Cited
1992
Highly Cited
1992
The effects of dexamethasone on fibronectin expression in cultured human trabecular meshwork cells.
Topical administration of glucocorticoids to the eye can lead to the development of ocular hypertension. This increase in… 
Highly Cited
1991
Highly Cited
1991
The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex.
The steroid 11 beta-hydroxylase (P450c11) enzyme is responsible for the conversion of 11-deoxycortisol to cortisol in the zona… 
Highly Cited
1991
Highly Cited
1991
Normative data for adrenal steroidogenesis in a healthy pediatric population: age- and sex-related changes after adrenocorticotropin stimulation.
The normal response to a single 0.25-mg dose of ACTH-(1-24) is not well established in infancy or childhood. We report the… 
Highly Cited
1981
Highly Cited
1981
Regulation of glucocorticoid receptors by glucocorticoids in cultured HeLa S3 cells.
HeLa S3 cells contain high affinity, saturable receptors specific for glucocorticoids (congruent to 20,000 per cell). Growth of… 
Highly Cited
1977
Highly Cited
1977
Glucocorticoid receptors and inhibition of bone cell growth in primary culture.
We have previously identified glucocorticoid binding proteins in cytosol of cells dispersed from fetal rat calvaria by… 
Highly Cited
1977
Highly Cited
1977
Immunosuppression by sex steroid hormones. The effect upon PHA- and PPD-stimulated lymphocytes.
Progesterone, estradiol, testosterone, cortisol, and 11-desoxycortisol (compound S) were added to cultures of human lymphocytes… 
Highly Cited
1973
Highly Cited
1973
Steroid-binding properties and stabilization of cytoplasmic glucocorticoid receptors from rat thymus cells.
1. A competitive binding assay was adapted for determination of the specific binding of glucocorticoids to cytoplasmic receptors… 
Highly Cited
1970
Highly Cited
1970
Male Pseudohermaphroditism Due to 17a -Hydroxylase Deficiency
Abstract This is the first report of a male with 17α-hydroxylase deficiency resulting in male pseudohermaphroditism, ambiguous… 
Highly Cited
1968
Highly Cited
1968
Specific and nonspecific physicochemical interactions of glucocorticoids and related steroids with rat thymus cells in vitro.
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