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Cortisone Reductase

Known as: 20 beta Hydroxysteroid Dehydrogenase, Dehydrogenase, 20-beta-Hydroxysteroid, Reductase, Cortisone 
An enzyme that catalyzes the interconversion of a ketone and hydroxy group at C-20 of cortisone and other 17,20,21-trihydroxy steroids. EC 1.1.1.53.
National Institutes of Health

Related topics

Related topics

8 relations

Broader (1)

Hydroxysteroid Dehydrogenases
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

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Review
2007
Review
2007
Hexose 6-phosphate dehydrogenase (H6PD) and corticosteroid metabolism
Highly Cited
2006
Highly Cited
2006
Uncoupled Redox Systems in the Lumen of the Endoplasmic Reticulum
The redox state of the intraluminal pyridine nucleotide pool was investigated in rat liver microsomal vesicles. The vesicles… 
2003
2003
11β-Hydroxysteroid Dehydrogenase Type 1 Deficiency (‘Apparent Cortisone Reductase Deficiency’) in a 6-Year-Old Boy
Objective: We present the 1st case of prepubertal hyperandrogenism because of a defect in the conversion of cortisone (E) to… 
2001
2001
Light and Electron Microscopy Localization of the 11β-Hydroxysteroid Dehydrogenase Type I Enzyme in the Rat.
The 11β-hydroxysteroid dehydrogenase type I enzyme (11βHSD1) converts cortisone to cortisol in humans, and 11… 
2000
2000
Apparent Cortisone Reductase Deficiency: A Rare Cause of Hyperandrogenemia and Hypercortisolism
A 55-year-old woman presented with androgenetic alopecia which had started at age 40. Her clinical history revealed that, unlike… 
Highly Cited
1996
Highly Cited
1996
Apparent cortisone reductase deficiency: a unique form of hypercortisolism.
We describe two female siblings who had production of cortisol (F; as determined from excretion of urinary metabolites) high… 
1990
1990
Demonstration of 3 alpha(17 beta)-hydroxysteroid dehydrogenase distinct from 3 alpha-hydroxysteroid dehydrogenase in hamster liver.
NAD(+)-linked and NADP(+)-linked 3 alpha-hydroxysteroid dehydrogenases were purified to homogeneity from hamster liver cytosol… 
1979
1979
Effects of tamoxifen on the binding and metabolism of testosterone by human prostatic tissue and plasma in vitro.
The in-vitro metabolism of testosterone in benign and malignant prostatic tissue was examined and distinct quantitative… 
1978
1978
Comparison of the 3alpha-and 20beta-hydroxysteroid dehydrogenase activities of the cortisone reductase of Streptomyces hydrogenans.
The 3alpha- and 20beta-hydroxysteroid dehydrogenase (HSD) activities of cortisone reductase in Streptomyces hydrogenans have been… 
1969
1969
A histochemical study of ovarian function in the ovoviviparous elasmobranch, Squalus acanthias.
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