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Cortisone Reductase

Known as: 20 beta Hydroxysteroid Dehydrogenase, Dehydrogenase, 20-beta-Hydroxysteroid, Reductase, Cortisone 
An enzyme that catalyzes the interconversion of a ketone and hydroxy group at C-20 of cortisone and other 17,20,21-trihydroxy steroids. EC 1.1.1.53.
National Institutes of Health

Related topics

Related topics

8 relations

Broader (1)

Hydroxysteroid Dehydrogenases
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

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2012
2012
Association study of CYP17 and HSD11B1 in polycystic ovary syndrome utilizing comprehensive gene coverage.
Cytochrome P450-C17 enzyme (CYP17) is an important component of the androgen synthesis pathway, a pathway that is dysfunctional… 
1990
1990
Demonstration of 3 alpha(17 beta)-hydroxysteroid dehydrogenase distinct from 3 alpha-hydroxysteroid dehydrogenase in hamster liver.
NAD(+)-linked and NADP(+)-linked 3 alpha-hydroxysteroid dehydrogenases were purified to homogeneity from hamster liver cytosol… 
1980
1980
Study of 3 alpha, 20 beta-hydroxysteroid dehydrogenase with an enzyme-generated affinity alkylator: dual enzyme activity at a single active site.
The substrate 17 beta-[(1S)-1-hydroxy-2-propynyl]-androst-4-en-3-one (beta-HPA) and its enzyme-generated alkylating product 17… 
1979
1979
Effects of tamoxifen on the binding and metabolism of testosterone by human prostatic tissue and plasma in vitro.
The in-vitro metabolism of testosterone in benign and malignant prostatic tissue was examined and distinct quantitative… 
1978
1978
Comparison of the 3alpha-and 20beta-hydroxysteroid dehydrogenase activities of the cortisone reductase of Streptomyces hydrogenans.
The 3alpha- and 20beta-hydroxysteroid dehydrogenase (HSD) activities of cortisone reductase in Streptomyces hydrogenans have been… 
1973
1973
3-Hydroxy steroid dehydrogenase activities of cortisone reductase.
The behaviour of various C(19) and C(18) steroids as substrates for crystalline preparations of cortisone reductase (EC 1.1.1.53… 
1973
1973
Affinity labeling of steroid binding sites. Study of the active site of 20-beta-hydroxysteroid dehydrogenase with 6-beta- and 11 alpha-bromoacetoxyprogesterone.
1973
1973
The steric course with respect to the reduced nicotinamide-adenine dinucleotide of the reduction of 3-oxo steroids catalysed by cortisone reductase.
The stereochemistry of hydrogen transfer from NADH during the reduction of the 3-oxo groups of various steroids by cortisone… 
1972
1972
Structural features of ring A and the interaction of 20-oxosteroids with cortisone reductase.
Kinetic mesurements were made using cortisone reductase and a series of substrates which differed in size, shape and electronic… 
1972
1972
Reduction of the non-steroid adamantanone by crystalline preparations of cortisone reductase.
Cortisone reductase (EC 1.1.1.53) has 20,Bhydroxy steroid-NADI oxidoreductase activity (Hubener & Lehmann, 1958) and 3-hydroxy… 
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