Complement Receptor Type 1

Known as: CD35, CD35 Antigen 
Complement receptor type 1 (2039 aa, ~224 kDa) is encoded by the human CR1 gene. This protein is involved in complement activation.
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Patients with systemic lupus erythematosus (SLE) have relative deficiencies of the C3b/C4b receptor (CR1, CD35) on erythrocytes… (More)
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2002
2002
The complement system---particularly component C3---has been demonstrated to be a key link between innate and adaptive immunity… (More)
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Review
2001
Review
2001
Human complement receptor type 1 (CR1) is a large, multifunctional glycoprotein which is a member of the regulators of complement… (More)
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Review
1998
Review
1998
Complement activation plays a critical role in the pathogenesis of many forms of glomerulonephritis. Complement activation leads… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Cancer patients treated with the anticancer drug, paclitaxel (Taxol) often experience mild to severe hypersensitivity… (More)
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1998
1998
Two functionally distinct but homologous sites in complement receptor type 1 (CR1) (CD35) were further characterized by… (More)
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Highly Cited
1997
Highly Cited
1997
Molecular definition of the cellular receptor for the collagen domain of C1q has been elusive. We now report that C1q binds… (More)
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1996
1996
A new approach has been used to extend the T(1/2) of human soluble complement receptor type 1 (sCR1) in rats. The albumin-binding… (More)
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Highly Cited
1992
Highly Cited
1992
We examined the role of C activation in ischemia reperfusion injury by inhibiting C activation in a rat model of mesenteric… (More)
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Highly Cited
1990
Highly Cited
1990
The complement system is an important mediator of the acute inflammatory response, and an effective inhibitor would suppress… (More)
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