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Complement Receptor Type 1

Known as: CD35, CD35 Antigen 
Complement receptor type 1 (2039 aa, ~224 kDa) is encoded by the human CR1 gene. This protein is involved in complement activation.
National Institutes of Health

Related topics

Related topics

8 relations
CR1 geneCR1 wt AlleleComplement 3b ReceptorComplement Activation

Broader (1)

Complement Receptor

Papers overview

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Highly Cited
1999
Highly Cited
1999
Antiinflammatory effects of soluble complement receptor type 1 promote rapid recovery of ischemia/reperfusion injury in rat small intestine.
We examined the effect of soluble complement receptor type 1 (sCR1) on mucosal injury and inflammation in a rat model of ischemia… 
Highly Cited
1999
Highly Cited
1999
Independently melting modules and highly structured intermodular junctions within complement receptor type 1.
A segment of complement receptor type 1 (CR1) corresponding to modules 15-17 was overexpressed as a functionally active… 
1999
1999
Protection of Baculovirus-Vectors against Complement-Mediated Inactivation by Recombinant Soluble Complement Receptor Type 1
Abstract Baculovirus-based vectors are efficient means for gene transfer into hepatocytes in vitro. However, gene transfer in… 
1998
1998
Soluble complement receptor type I limits damage during revascularization of ischemic myocardium.
1997
1997
Complement activation in vitro by the red cell substitute, liposome‐ encapsulated hemoglobin: mechanism of activation and inhibition by soluble complement receptor type 1
BACKGROUND: Liposome‐encapsulated hemoglobin (LEH) has been developed as an emergency blood substitute, yet its effect on human… 
Review
1990
Review
1990
Complement receptor type 1 (C3b/C4b receptor; CD35) and complement receptor type 2 (C3d/Epstein-Barr virus receptor; CD21).
The primary sequence of the A allotype of CR1 has been deduced from the cDNA sequence and includes a 41-residue signal peptide… 
Highly Cited
1987
Highly Cited
1987
Erythrocytes transfused into patients with SLE and haemolytic anaemia lose complement receptor type 1 from their cell surface.
Erythrocyte complement receptor type 1 (CR1) shows a numerical deficiency in patients with SLE and with haemolytic anaemias. This… 
Highly Cited
1987
Highly Cited
1987
Inherited deficiency of erythrocyte complement receptor type 1 does not cause susceptibility to systemic lupus erythematosus.
There is a deficiency of complement receptor type 1 (CR1) on the erythrocytes of patients with systemic lupus erythematosus (SLE… 
Highly Cited
1986
Highly Cited
1986
Loss of complement receptor type 1 (CR1) on ageing of erythrocytes. Studies of proteolytic release of the receptor.
Complement receptor type 1 (CR1) is a glycoprotein of Mr about 250 000 present on erythrocytes and other cell types. CR1 acts as… 
1984
1984
Analysis of C3-receptor activity on human B-lymphocytes and isolation of the complement receptor type 2 (CR2).
The rosetting of defined C3-fragment-coated sheep erythrocytes to B-cell-enriched tonsil lymphocytes was measured. The rosetting… 
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