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Complement Receptor Type 1

Known as: CD35, CD35 Antigen 
Complement receptor type 1 (2039 aa, ~224 kDa) is encoded by the human CR1 gene. This protein is involved in complement activation.
National Institutes of Health

Related topics

Related topics

8 relations
CR1 geneCR1 wt AlleleComplement 3b ReceptorComplement Activation

Broader (1)

Complement Receptor

Papers overview

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2006
2006
Preclinical evaluation of the neuroprotective effect of soluble complement receptor type 1 in a nonhuman primate model of reperfused stroke.
OBJECT Postischemic cerebral inflammatory injury has been extensively investigated in an effort to develop effective… 
1999
1999
Protection of Baculovirus-Vectors against Complement-Mediated Inactivation by Recombinant Soluble Complement Receptor Type 1
Abstract Baculovirus-based vectors are efficient means for gene transfer into hepatocytes in vitro. However, gene transfer in… 
1999
1999
The C3b/C4b receptor (CR1, CD35) on erythrocytes: methods for study of the polymorphisms.
1997
1997
Complement activation in vitro by the red cell substitute, liposome‐ encapsulated hemoglobin: mechanism of activation and inhibition by soluble complement receptor type 1
BACKGROUND: Liposome‐encapsulated hemoglobin (LEH) has been developed as an emergency blood substitute, yet its effect on human… 
Review
1990
Review
1990
Complement receptor type 1 (C3b/C4b receptor; CD35) and complement receptor type 2 (C3d/Epstein-Barr virus receptor; CD21).
The primary sequence of the A allotype of CR1 has been deduced from the cDNA sequence and includes a 41-residue signal peptide… 
Highly Cited
1987
Highly Cited
1987
Erythrocytes transfused into patients with SLE and haemolytic anaemia lose complement receptor type 1 from their cell surface.
Erythrocyte complement receptor type 1 (CR1) shows a numerical deficiency in patients with SLE and with haemolytic anaemias. This… 
Highly Cited
1987
Highly Cited
1987
Inherited deficiency of erythrocyte complement receptor type 1 does not cause susceptibility to systemic lupus erythematosus.
There is a deficiency of complement receptor type 1 (CR1) on the erythrocytes of patients with systemic lupus erythematosus (SLE… 
Highly Cited
1987
Highly Cited
1987
Quantitative analyses of the binding of soluble complement-fixing antibody/dsDNA immune complexes to CR1 on human red blood cells.
We have used direct binding isotherm analyses to measure the association constant (Ka) and number of binding sites for the… 
Highly Cited
1986
Highly Cited
1986
Loss of complement receptor type 1 (CR1) on ageing of erythrocytes. Studies of proteolytic release of the receptor.
Complement receptor type 1 (CR1) is a glycoprotein of Mr about 250 000 present on erythrocytes and other cell types. CR1 acts as… 
1984
1984
Analysis of C3-receptor activity on human B-lymphocytes and isolation of the complement receptor type 2 (CR2).
The rosetting of defined C3-fragment-coated sheep erythrocytes to B-cell-enriched tonsil lymphocytes was measured. The rosetting… 
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