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CR1 gene

Known as: C3BR, C4BR, CR1 
This gene is involved in the complement activation pathway.
National Institutes of Health

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CR1 wt Allele
Complement ActivationComplement Receptor Type 1Knops blood group system

Papers overview

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Highly Cited
1994
Highly Cited
1994
Sequence-specific DNA binding of individual cut repeats of the human CCAAT displacement/cut homeodomain protein.
CCAAT displacement protein (CDP), a nuclear protein of 180-190 kDa, contains a triplicated motif, the cut domain, similar (80-90… 
Highly Cited
1989
Highly Cited
1989
Distribution in clusters of complement receptor type one (CR1) on human erythrocytes.
The distribution of CR1 on human E was studied using label-fracture and thin section electron microscopy. CR1 was found to be… 
Highly Cited
1986
Highly Cited
1986
Loss of complement receptor type 1 (CR1) on ageing of erythrocytes. Studies of proteolytic release of the receptor.
Complement receptor type 1 (CR1) is a glycoprotein of Mr about 250 000 present on erythrocytes and other cell types. CR1 acts as… 
Highly Cited
1986
Highly Cited
1986
Tissue-specific phosphorylation of complement receptors CR1 and CR2
CR1 of neutrophils and monocytes may exist in a resting state, in which it only binds ligand-coated particles, or an activated… 
Highly Cited
1985
Highly Cited
1985
Disease-associated loss of erythrocyte complement receptors (CR1, C3b receptors) in patients with systemic lupus erythematosus and other diseases involving autoantibodies and/or complement activation…
Although surface membrane density of complement receptor type one (CR1) on erythrocytes (E) is probably an inherited trait among… 
Highly Cited
1985
Highly Cited
1985
Characterization of a soluble form of the C3b/C4b receptor (CR1) in human plasma.
A radioimmunoassay with the use of soluble 125I-Fab monoclonal anti-CR1 and rabbit IgG anti-CR1 bound to Staphylococcus aureus… 
Highly Cited
1985
Highly Cited
1985
Polymorphism of the C3b/C4b receptor (CR1): characterization of a fourth allele.
The receptor for C3b/C4b (C3bR or CR1) has an unusual polymorphism in which three codominant alleles determine variants with a… 
Highly Cited
1984
Highly Cited
1984
Immunoglobulin production by human peripheral lymphocytes induced by anti-C3 receptor antibodies.
The exact function of receptors for C3b (CR1), which are present on B lymphocytes, is not clear. The present studies were… 
Highly Cited
1984
Highly Cited
1984
Polymorphism of the human C3b/C4b receptor. Identification of a third allele and analysis of receptor phenotypes in families and patients with systemic lupus erythematosus
We have isolated C3bR from surface-labeled erythrocytes of 180 normal individuals and 45 patients with SLE. These studies have… 
Highly Cited
1982
Highly Cited
1982
Complement receptor (CR1) deficiency in erythrocytes from patients with systemic lupus erythematosus
This study reports quantitative information on the concentration of complement receptor for C3b and C4b (CR1) on erythrocytes… 
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