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CR1 gene

Known as: C3BR, C4BR, CR1 
This gene is involved in the complement activation pathway.
National Institutes of Health

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CR1 wt Allele
Complement ActivationComplement Receptor Type 1Knops blood group system

Papers overview

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Highly Cited
1998
Highly Cited
1998
Mapping epitopes for 20 monoclonal antibodies to CR1
Complement receptor type one (CR1; CD35) binds and processes C3b and C4b opsonized immune complexes and regulates complement… 
Highly Cited
1996
Highly Cited
1996
The CtBP binding domain in the adenovirus E1A protein controls CR1- dependent transactivation
The adenovirus E1A-243R protein has the ability to force a resting cell into uncontrolled proliferation by modulating the… 
Highly Cited
1994
Highly Cited
1994
Sequence-specific DNA binding of individual cut repeats of the human CCAAT displacement/cut homeodomain protein.
CCAAT displacement protein (CDP), a nuclear protein of 180-190 kDa, contains a triplicated motif, the cut domain, similar (80-90… 
Highly Cited
1989
Highly Cited
1989
Distribution in clusters of complement receptor type one (CR1) on human erythrocytes.
The distribution of CR1 on human E was studied using label-fracture and thin section electron microscopy. CR1 was found to be… 
Highly Cited
1986
Highly Cited
1986
Loss of complement receptor type 1 (CR1) on ageing of erythrocytes. Studies of proteolytic release of the receptor.
Complement receptor type 1 (CR1) is a glycoprotein of Mr about 250 000 present on erythrocytes and other cell types. CR1 acts as… 
Highly Cited
1986
Highly Cited
1986
Tissue-specific phosphorylation of complement receptors CR1 and CR2
CR1 of neutrophils and monocytes may exist in a resting state, in which it only binds ligand-coated particles, or an activated… 
Highly Cited
1985
Highly Cited
1985
Disease-associated loss of erythrocyte complement receptors (CR1, C3b receptors) in patients with systemic lupus erythematosus and other diseases involving autoantibodies and/or complement activation…
Although surface membrane density of complement receptor type one (CR1) on erythrocytes (E) is probably an inherited trait among… 
Highly Cited
1985
Highly Cited
1985
Characterization of a soluble form of the C3b/C4b receptor (CR1) in human plasma.
A radioimmunoassay with the use of soluble 125I-Fab monoclonal anti-CR1 and rabbit IgG anti-CR1 bound to Staphylococcus aureus… 
Highly Cited
1985
Highly Cited
1985
Polymorphism of the C3b/C4b receptor (CR1): characterization of a fourth allele.
The receptor for C3b/C4b (C3bR or CR1) has an unusual polymorphism in which three codominant alleles determine variants with a… 
Highly Cited
1984
Highly Cited
1984
Polymorphism of the human C3b/C4b receptor. Identification of a third allele and analysis of receptor phenotypes in families and patients with systemic lupus erythematosus
We have isolated C3bR from surface-labeled erythrocytes of 180 normal individuals and 45 patients with SLE. These studies have… 
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