Complement C3 Convertases

Known as: Convertase, C 3, Convertases, Complement C3, Convertase, C3 
Serine proteases that cleaves C3 at the carboxyl of Arg-77 of the alpha-chain to yield COMPLEMENT 3A and COMPLEMENT 3B in either the classical or the… (More)
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Molecular linkages between von Willebrand factor (VWF) and the alternative complement pathway (AP) have recently been discovered… (More)
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2012
2012
Human complement factor H-related protein (CFHR) 4 belongs to the factor H family of plasma glycoproteins that are composed of… (More)
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Review
2012
Review
2012
During the last decade, numerous studies have associated genetic variations in complement components and regulators with a number… (More)
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1995
1995
The herpesvirus saimiri genome encodes a complement control protein homolog (CCPH). Stable mammalian cell transfectants… (More)
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Highly Cited
1986
Highly Cited
1986
The association of Factor B with C3b (the major fragment of complement component C3) in the presence of Mg2+ results in the… (More)
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1981
1981
A protein with decay-accelerating activity for the classical C3 convertase, C4b2a, has been isolated on the basis of this… (More)
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1980
1980
The assembly of the classical pathway C3 convertase in the fluid phase has been studied. The enzyme is assembled from C2 and C4… (More)
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Highly Cited
1979
Highly Cited
1979
We recently described the isolation from human serum of a serum protein (C4 binding protein) that functions as an essential… (More)
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Highly Cited
1979
Highly Cited
1979
An activity that is inhibitory to the properdin-stabilized amplification C3 convertase (C3b,Bb,P) was solubilized from human… (More)
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1975
1975
Two complex enzymes were assembled that both converted C3 to C3b, one consisting of activated properdin (P), native C3… (More)
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