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Complement C3 Convertases

Known as: Convertase, C 3, Convertases, Complement C3, Convertase, C3 
Serine proteases that cleaves C3 at the carboxyl of Arg-77 of the alpha-chain to yield COMPLEMENT 3A and COMPLEMENT 3B in either the classical or the… 
National Institutes of Health

Related topics

Related topics

8 relations
Complement 3b InactivatorsComplement C1qComplement C4bComplement C5 Convertases

Narrower (1)

Complement C3 Convertase, Alternative Pathway

Broader (1)

Complement C3-C5 Convertases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Aurin tricarboxylic acid self-protects by inhibiting aberrant complement activation at the C3 convertase and C9 binding stages
2012
2012
By low molecular weight components of aurintricarboxylic acid synthesis complex, selective inhibition of membrane attack complex and c3 convertase of complement
With molecular weight of kilodalton less components aurintricarboxylic acid complex, mammalian species, preferably selectively… 
1986
1986
A model system for the study of the assembly and regulation of human complement C3 convertase (classical pathway)
The formation of classical C3 convertase of complement and its regulation by C4b‐binding protein (C4bp) were studied using two… 
Highly Cited
1982
Highly Cited
1982
Modulation of classical C3 convertase of complement by tear lactoferrin.
Lactoferrin isolated fom normal human tears was shown to inhibit the complement-mediated lysis of antibody-coated red cells. The… 
1981
1981
Modulation of the formation of the human amplification c 3 convertase by poly cations
1980
1980
Membrane specific igg augments the generation of membrane bound amplification c3 convertase sites with purified proteins. Abstr.
Review
1977
Review
1977
Pathways of complement activation in membranoproliferative glomerulonephritis and allograft rejection.
The complement system is comprised of at least 18 plasma proteins and consists of four functional divisions: two pathways for… 
1976
1976
The cofactors required by C3 nephritic factor to generate a C3 convertase in vitro.
The mechanisms by which a C3 convertase is generated by C3 nephritic factor (NeF) were investigated using purified NeF, C3, C3b… 
1975
1975
Alternate complement pathway induction of aggregation and release of 5-hydroxytryptamine and adenosine diphosphate by rabbit platelets.
The present studies investigated patterns of rabbit platelet aggregation and release of 5-hydroxytryptamine (5HT) utilizing nine… 
1974
1974
Purification of human C3 proactivator by affinity chromatography.
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