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Complement C3 Convertases

Known as: Convertase, C 3, Convertases, Complement C3, Convertase, C3 
Serine proteases that cleaves C3 at the carboxyl of Arg-77 of the alpha-chain to yield COMPLEMENT 3A and COMPLEMENT 3B in either the classical or the… Expand
National Institutes of Health

Papers overview

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Review
2012
Review
2012
During the last decade, numerous studies have associated genetic variations in complement components and regulators with a number… Expand
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Highly Cited
2012
Highly Cited
2012
Background: Complement factor H-related protein 4 (CFHR4) has been shown to interact with C3b. Results: Binding of C3b to CFHR4… Expand
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Highly Cited
2002
Highly Cited
2002
The AP C3 convertase, C3bBb(Mg2+), is subject to irreversible dissociation (decay acceleration) by three proteins: DAF, CR1, and… Expand
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Highly Cited
1995
Highly Cited
1995
The herpesvirus saimiri genome encodes a complement control protein homolog (CCPH). Stable mammalian cell transfectants… Expand
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Highly Cited
1986
Highly Cited
1986
The association of Factor B with C3b (the major fragment of complement component C3) in the presence of Mg2+ results in the… Expand
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Highly Cited
1980
Highly Cited
1980
  • M. Kerr
  • The Biochemical journal
  • 1980
  • Corpus ID: 24619869
The assembly of the classical pathway C3 convertase in the fluid phase has been studied. The enzyme is assembled from C2 and C4… Expand
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Highly Cited
1979
Highly Cited
1979
  • D. Fearon
  • Proceedings of the National Academy of Sciences…
  • 1979
  • Corpus ID: 41604472
An activity that is inhibitory to the properdin-stabilized amplification C3 convertase (C3b,Bb,P) was solubilized from human… Expand
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Highly Cited
1979
Highly Cited
1979
We recently described the isolation from human serum of a serum protein (C4 binding protein) that functions as an essential… Expand
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Highly Cited
1975
Highly Cited
1975
Two complex enzymes were assembled that both converted C3 to C3b, one consisting of activated properdin (P), native C3… Expand
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Highly Cited
1974
Highly Cited
1974
Properdin (P), a highly basic euglobulin, was purified from human serum to molecular homogeneity without the use of zymosan… Expand
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