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Complement C5 Convertases

Known as: C5 Convertases, Complement, Convertases, Complement C5, C5 Convertase 
Serine proteases that cleaves C5 at the carboxyl of Arg-74 of the alpha-chain to yield COMPLEMENT 5A and COMPLEMENT 5B in either the classical or the… 
National Institutes of Health

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Related topics

2 relations
Complement C3 Convertases

Broader (1)

Complement C3-C5 Convertases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Molecular and expression analysis of complement component C5 in the nurse shark (Ginglymostoma cirratum) and its predicted functional role.
2001
2001
Localization of the Covalent C 3 b-binding Site on C 4 b within the Complement Classical Pathway C 5 Convertase , C 4 b 2 a 3 b *
C5 convertase of the classical complement pathway is a trimolecular protein complex consisting of C4b, CZa, and C3b. In the… 
1984
1984
Protection of the classical and alternative complement pathway C3 convertases, stabilized by nephritic factors, from decay by the human C3b receptor
Formation and function of the classical (C4b, 2a) and alternative (C3b, Bb) complement pathway C3 convertases are regulated by… 
1983
1983
Surface-dependent modulation by H of C5 cleavage by the cell-bound alternative pathway C5 convertase of human complement.
Regulation by H of formation of the C3 and C5 alternative pathway convertases of complement on cells is dependent on such… 
1983
1983
Inhibition of classical C5 convertase in the complement system by factor H.
This paper described the influence of factor H on the haemolytic activity of the classical C5 convertase. Factor H showed little… 
1978
1978
Inhibition of C5 convertase by epsilon amino caproic acid (EACA): a limiting factor in the generation of C5a anaphylatoxin.
The effect of EACA on spontaneous C5 consumption and on the mechanisms of C5 activation through the alternative pathway of… 
Highly Cited
1976
Highly Cited
1976
C3 requirements for formation of alternative pathway C5 convertase.
Although alternative pathway C3 and C5 convertases both have active proteolytic sites dependent on the same protein, Bb, the… 
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