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Clemastine
Known as:
Meclastin
, Mecloprodin
, Clemastina
Â
(More)
A histamine H1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
National Institutes of Health
Topic mentions per year
Topic mentions per year
1963-2018
0
5
10
1963
2018
Related topics
Related topics
19 relations
Angle Closure Glaucoma
Clemastine Fumarate
Drug Allergy
In Blood
(More)
Broader (3)
Anti-Allergic Agents
Antipruritics
Histamine H1 Antagonists
Narrower (3)
HS-592
Tavegyl
Tavist
Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
Clemastine
Drug Allergy
agonists
Urticaria
chemical synthesis
Histamine H1 Antagonists
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice.
Jia Liu
,
Jeffrey L Dupree
,
+4 authors
Patrizia Casaccia
The Journal of neuroscience : the official…
2016
Altered myelin structure and oligodendrocyte function have been shown to correlate with cognitive and motor dysfunction and…Â
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2011
2011
Clemastine potentiates the human P2X7 receptor by sensitizing it to lower ATP concentrations.
Wolfgang Nörenberg
,
Christoph Hempel
,
Nicole Urban
,
Helga Sobottka
,
Péter Illés
,
Michael Schaefer
The Journal of biological chemistry
2011
P2X7 receptors have emerged as potential drug targets for the treatment of medical conditions such as e.g. rheumatoid arthritis…Â
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Highly Cited
2005
Highly Cited
2005
Rituximab treatment in patients with primary Sjögren's syndrome: an open-label phase II study.
Jeroen Pijpe
,
Gustaaf W. van Imhoff
,
+6 authors
Hester H J Bootsma
Arthritis and rheumatism
2005
OBJECTIVE To investigate the safety and efficacy of B cell depletion treatment of patients with active primary Sjögren's syndrome…Â
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1997
1997
Effectiveness of clemastine fumarate for treatment of rhinorrhea and sneezing associated with the common cold.
Ronald B. Turner
,
Saskia Sperber
,
+4 authors
Jack M. Gwaltney
Clinical infectious diseases : an official…
1997
Limited data support the use of first-generation antihistamines for treatment of the common cold. The purpose of this study was…Â
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1994
1994
Effects of mizolastine and clemastine on actual driving and psychomotor performance in healthy volunteers
E. F. P. M. Vuurman
,
Marcelle Uiterwijk
,
J F O'hanlon
,
Phil Rosenzweig
European Journal of Clinical Pharmacology
1994
The acute effect of doses of mizolastine 5, 10, 20 and 40 mg, an active control (clemastine 2 mg) and placebo on actual car…Â
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1994
1994
Risk of developing life-threatening ventricular arrhythmia associated with tefenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine.
Craig M. Pratt
,
Rivka Hertz
,
Brian Ellis
,
Sherry Crowell
,
William C. Louv
,
Lew Moye
The American journal of cardiology
1994
An observational, historical cohort evaluation was performed to examine the hypothesis that terfenadine (Seldane) exposure…Â
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1989
1989
Clinical evaluation of ketotifen for chronic urticaria: multicenter double-blind comparative study with clemastine.
Ryoichi Kamide
,
Manabu Niimura
,
+4 authors
Akiko Kukita
Annals of allergy
1989
A double-blind study was performed in 305 patients to compare ketotifen capsule and clemastine tablet. Ketotifen alleviated…Â
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1981
1981
Bronchodilator effects of clemastine, ipratropium, bromide, and salbutamol in preschool children with asthma.
R C Groggins
,
Angela Milner
,
Gerald M. Stokes
Archives of disease in childhood
1981
The bronchodilator activity in nebulised salbutamol, ipratropium bromide, clemastine, and a placebo was studied in 14 asthmatic…Â
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1978
1978
Bronchodilatation after inhalation of the antihistamine clemastine.
S G Nogrady
,
Judith Hartley
,
Peter Handslip
,
Nicholas Hurst
Thorax
1978
H1 receptor blocking antihistamines administered by mouth have not found a clear place in the management of bronchial asthma. We…Â
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1975
1975
Evaluation ofin vivo parameters of drug metabolizing enzyme activity in man after administration of clemastine, phenobarbital or placebo
Andreas Hildebrandt
,
Ivar Roots
,
Maren E. Speck
,
K. Saalfrank
,
Helmut Kewitz
European Journal of Clinical Pharmacology
1975
The 24 h urinary excretion of 6β-hydroxycortisol and D-glucaric acid, the plasma half-lives and total clearances of aminopyrine…Â
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