Chromatin Structure

The more readily stainable portion of the cell nucleus, forming a network of nuclear fibrils within the achromatin of a cell. It is a… (More)
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Chromatin immunoprecipitation coupled with high-throughput sequencing (ChIP-seq) has become the dominant technique for mapping… (More)
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Highly Cited
2009
Highly Cited
2009
An increasing body of evidence indicates that transcription and splicing are coupled, and it is accepted that chromatin… (More)
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Highly Cited
2006
Highly Cited
2006
Acetylation of histone H4 on lysine 16 (H4-K16Ac) is a prevalent and reversible posttranslational chromatin modification in… (More)
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Highly Cited
2006
Highly Cited
2006
The family of myc proto-oncogenes encodes transcription factors (c-, N-, and L-Myc) that regulate cell growth and proliferation… (More)
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Highly Cited
2004
Highly Cited
2004
The covalent modification of nucleosomal histones has emerged as a major determinant of chromatin structure and gene activity. To… (More)
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Highly Cited
2004
Highly Cited
2004
The colinearity of genes in Hox clusters suggests a role for chromosome structure in gene regulation. We reveal programmed… (More)
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Highly Cited
2000
Highly Cited
2000
The organization of chromatin into higher-order structures influences chromosome function and epigenetic gene regulation. Higher… (More)
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Highly Cited
1998
Highly Cited
1998
Differentiating cells undergo programmed alterations in their patterns of gene expression, which are often regulated by… (More)
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Review
1997
Review
1997
The amino termini of histones extend from the nucleosomal core and are modified by acetyltransferases and deacetylases during the… (More)
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Highly Cited
1997
Highly Cited
1997
Recent advances leave no doubt that higher order chromatin structures play a fundamental role in many developmentally important… (More)
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