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Chromatin Assembly Factor-1, human

Known as: Chromatin Assembly Factor I Complex, Chromatin Assembly Factor 1 Complex, CAF-I 
A heterotrimeric protein complex that mediates chromatin assembly by promoting histone H3 and H4 deposition onto newly synthesized DNA during… 
National Institutes of Health

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Related topics

6 relations
CAF-1 complex locationChromatin Assembly Factor 1 Subunit AChromatin Remodeling FactorHistone-Binding Protein RBBP4
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Broader (1)

Chromatin Assembly Factor-1

Papers overview

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Highly Cited
2015
Highly Cited
2015
Cell cycle regulation of human DNA repair and chromatin remodeling genes.
Maintenance of a genome requires DNA repair integrated with chromatin remodeling. We have analyzed six transcriptome data sets… 
Highly Cited
2011
Highly Cited
2011
Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin
The carbon catabolite repressor protein 4 (Ccr4)–Negative on TATA (Not) complex controls gene expression at two levels. In the… 
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Highly Cited
2001
Highly Cited
2001
Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing
BACKGROUND Position-dependent gene silencing in yeast involves many factors, including the four HIR genes and nucleosome assembly… 
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Highly Cited
2000
Highly Cited
2000
A CAF-1–PCNA-Mediated Chromatin Assembly Pathway Triggered by Sensing DNA Damage
ABSTRACT Sensing DNA damage is crucial for the maintenance of genomic integrity and cell cycle progression. The participation of… 
Review
1999
Review
1999
Chromatin assembly: biochemical identities and genetic redundancy.
Investigations on chromatin assembly in vitro implicate chromatin assembly factor 1 (CAF1) as a chaperone for histones H3/H4 and… 
Highly Cited
1999
Highly Cited
1999
Role of Saccharomyces cerevisiae chromatin assembly factor-I in repair of ultraviolet radiation damage in vivo.
In vitro, the protein complex Chromatin Assembly Factor-I (CAF-I) from human or yeast cells deposits histones onto DNA templates… 
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Highly Cited
1998
Highly Cited
1998
Hir Proteins Are Required for Position-Dependent Gene Silencing in Saccharomyces cerevisiae in the Absence of Chromatin Assembly Factor I
  • P. Kaufman, Jennifer L. Cohen, M. Osley
  • Molecular and Cellular Biology
  • 1998
  • Corpus ID: 23513791
ABSTRACT Chromatin assembly factor I (CAF-I) is a three-subunit histone-binding complex conserved from the yeast Saccharomyces… 
Highly Cited
1998
Highly Cited
1998
Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci.
CAC1/RLF2 encodes the largest subunit of chromatin assembly factor I (CAF-I), a complex that assembles newly synthesized histones… 
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Highly Cited
1996
Highly Cited
1996
Postreplicative chromatin assembly by Drosophila and human chromatin assembly factor 1
To study the relationship between DNA replication and chromatin assembly, we have purified a factor termed Drosophila chromatin… 
Highly Cited
1989
Highly Cited
1989
Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro
The purification and characterization of a replication-dependent chromatin assembly factor (CAF-I) from the nuclei of human cells… 
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