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Chromatin Assembly Factor-1, human

Known as: Chromatin Assembly Factor I Complex, Chromatin Assembly Factor 1 Complex, CAF-I 
A heterotrimeric protein complex that mediates chromatin assembly by promoting histone H3 and H4 deposition onto newly synthesized DNA during… Expand
National Institutes of Health

Related topics

Related topics

6 relations
CAF-1 complex locationChromatin Assembly Factor 1 Subunit AChromatin Remodeling FactorHistone-Binding Protein RBBP4
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Broader (1)

Chromatin Assembly Factor-1

Papers overview

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Highly Cited
2011
Highly Cited
2011
Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin
The carbon catabolite repressor protein 4 (Ccr4)–Negative on TATA (Not) complex controls gene expression at two levels. In the… Expand
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Highly Cited
2007
Highly Cited
2007
A novel role for histone chaperones CAF‐1 and Rtt106p in heterochromatin silencing
The histone chaperones CAF‐1 and Rtt106p are required for heterochromatin silencing in the yeast Saccharomyces cerevisiae… Expand
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Highly Cited
2001
Highly Cited
2001
Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing
BACKGROUND Position-dependent gene silencing in yeast involves many factors, including the four HIR genes and nucleosome assembly… Expand
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Highly Cited
2001
Highly Cited
2001
Dimerization of the largest subunit of chromatin assembly factor 1: importance in vitro and during Xenopus early development
To date, the in vivo importance of chromatin assembly factors during development in vertebrates is unknown. Chromatin assembly… Expand
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Highly Cited
2000
Highly Cited
2000
A CAF-1–PCNA-Mediated Chromatin Assembly Pathway Triggered by Sensing DNA Damage
ABSTRACT Sensing DNA damage is crucial for the maintenance of genomic integrity and cell cycle progression. The participation of… Expand
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Review
1999
Review
1999
Chromatin assembly: biochemical identities and genetic redundancy.
Investigations on chromatin assembly in vitro implicate chromatin assembly factor 1 (CAF1) as a chaperone for histones H3/H4 and… Expand
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Highly Cited
1998
Highly Cited
1998
Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci.
CAC1/RLF2 encodes the largest subunit of chromatin assembly factor I (CAF-I), a complex that assembles newly synthesized histones… Expand
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Highly Cited
1998
Highly Cited
1998
Hir Proteins Are Required for Position-Dependent Gene Silencing in Saccharomyces cerevisiae in the Absence of Chromatin Assembly Factor I
ABSTRACT Chromatin assembly factor I (CAF-I) is a three-subunit histone-binding complex conserved from the yeast Saccharomyces… Expand
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Highly Cited
1996
Highly Cited
1996
Postreplicative chromatin assembly by Drosophila and human chromatin assembly factor 1.
To study the relationship between DNA replication and chromatin assembly, we have purified a factor termed Drosophila chromatin… Expand
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Highly Cited
1989
Highly Cited
1989
Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro
The purification and characterization of a replication-dependent chromatin assembly factor (CAF-I) from the nuclei of human cells… Expand
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