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Chromatin Assembly Factor-1, human

Known as: Chromatin Assembly Factor I Complex, Chromatin Assembly Factor 1 Complex, CAF-I 
A heterotrimeric protein complex that mediates chromatin assembly by promoting histone H3 and H4 deposition onto newly synthesized DNA during… 
National Institutes of Health

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Related topics

6 relations
CAF-1 complex locationChromatin Assembly Factor 1 Subunit AChromatin Remodeling FactorHistone-Binding Protein RBBP4

Broader (1)

Chromatin Assembly Factor-1

Papers overview

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Highly Cited
2007
Highly Cited
2007
A novel role for histone chaperones CAF‐1 and Rtt106p in heterochromatin silencing
The histone chaperones CAF‐1 and Rtt106p are required for heterochromatin silencing in the yeast Saccharomyces cerevisiae… 
Highly Cited
2006
Highly Cited
2006
Chromatin assembly factor CAF-1 is required for cellular differentiation during plant development
Chromatin assembly factor CAF-1 facilitates the formation of nucleosomes on newly replicated DNA in vitro. However, the role of… 
Highly Cited
2006
Highly Cited
2006
Functional Genomic Analysis of CAF-1 Mutants in Arabidopsis thaliana*
Duplication of chromatin following DNA replication requires spatial reorganization of chromatin domains assisted by chromatin… 
Highly Cited
2003
Highly Cited
2003
The Methyl-CpG Binding Protein MBD1 Interacts with the p150 Subunit of Chromatin Assembly Factor 1
ABSTRACT DNA promoter hypermethylation has been shown to be a functional mechanism of transcriptional repression. This epigenetic… 
Highly Cited
2001
Highly Cited
2001
The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae.
The acetylation state of histones plays a central role in determining gene expression in chromatin. The reestablishment of the… 
Highly Cited
2001
Highly Cited
2001
Dimerization of the largest subunit of chromatin assembly factor 1: importance in vitro and during Xenopus early development
To date, the in vivo importance of chromatin assembly factors during development in vertebrates is unknown. Chromatin assembly… 
Highly Cited
2000
Highly Cited
2000
A CAF-1–PCNA-Mediated Chromatin Assembly Pathway Triggered by Sensing DNA Damage
ABSTRACT Sensing DNA damage is crucial for the maintenance of genomic integrity and cell cycle progression. The participation of… 
Review
1999
Review
1999
Chromatin assembly: biochemical identities and genetic redundancy.
Highly Cited
1996
Highly Cited
1996
Postreplicative chromatin assembly by Drosophila and human chromatin assembly factor 1
To study the relationship between DNA replication and chromatin assembly, we have purified a factor termed Drosophila chromatin… 
Highly Cited
1989
Highly Cited
1989
Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro
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