FAQ

Chromatin Assembly Factor 1 Subunit A

Known as: CAF-I p150, CAF-I 150 kDa Subunit, hp150 
Chromatin assembly factor 1 subunit A (956 aa, ~107 kDa) is encoded by the human CHAF1A gene. This protein plays a role in replication-dependent… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2015
01219892015

Related topics

Related topics

10 relations
BTG Cell Cycle Regulation PathwayCHAF1A geneCell NucleusChromatin Assembly Factor-1, human
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Chromatin Assembly Factor 1 Subunit A
Transcription, Genetic
DNA Replication
Cell Nucleus
Transcriptional Regulation
Genes, Regulator

Papers overview

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2015
2015
The histone chaperone CAF-1 safeguards somatic cell identity
Cellular differentiation involves profound remodelling of chromatic landscapes, yet the mechanisms by which somatic cell identity… (More)
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2007
2007
The Werner syndrome protein is required for recruitment of chromatin assembly factor 1 following DNA damage
The Werner syndrome protein (WRN) and chromatin assembly factor 1 (CAF-1) are both involved in the maintenance of genome… (More)
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2004
2004
Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1.
Bloom's syndrome (BS) is a genomic instability disorder characterized by cancer susceptibility. The protein defective in BS, BLM… (More)
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Highly Cited
2002
Highly Cited
2002
Chromatin assembly factor I mutants defective for PCNA binding require Asf1/Hir proteins for silencing.
Chromatin assembly factor I (CAF-I) is a conserved histone H3/H4 deposition complex. Saccharomyces cerevisiae mutants lacking CAF… (More)
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Highly Cited
2001
Highly Cited
2001
The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae.
The acetylation state of histones plays a central role in determining gene expression in chromatin. The reestablishment of the… (More)
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1999
1999
A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae.
The Sin3-Rpd3 histone deacetylase complex, conserved between human and yeast, represses transcription when targeted by promoter… (More)
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Highly Cited
1998
Highly Cited
1998
Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I.
Chromatin assembly factor I (CAF-I) is a three-subunit histone-binding complex conserved from the yeast Saccharomyces cerevisiae… (More)
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Highly Cited
1997
Highly Cited
1997
Intimin-dependent binding of enteropathogenic Escherichia coli to host cells triggers novel signaling events, including tyrosine phosphorylation of phospholipase C-gamma1.
Enteropathogenic Escherichia coli (EPEC) interactions with HeLa epithelial cells induced the tyrosine phosphorylation of a host… (More)
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Highly Cited
1991
Highly Cited
1991
Stepwise assembly of chromatin during DNA replication in vitro.
A cell free system that supports replication-dependent chromatin assembly has been used to determine the mechanism of histone… (More)
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Highly Cited
1989
Highly Cited
1989
Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro.
The purification and characterization of a replication-dependent chromatin assembly factor (CAF-I) from the nuclei of human cells… (More)
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