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α-Synuclein (α-syn), a protein implicated in Parkinson's disease pathogenesis, is a presynaptic protein suggested to regulate… Expand 1. The calcium binding capacity (kappa S) of bovine chromaffin cells preloaded with fura‐2 was measured during nystatin… Expand 1. Digital imaging and photometry were used in conjunction with the fluorescent Ca2+ indicator, Fura‐2, to examine intracellular… Expand I N synapses, a rise in presynaptic intracellular calcium leads to secretory vesicle fusion in less than a millisecond, as… Expand Secretion of catecholamines from single bovine chromaffin cells in culture was elicited by brief pressure ejections from a… Expand The capacitance of the surface membrane of small adrenal chromaffin cells was measured with patch-clamp pipettes. Continuous and… Expand 1. Inward currents in chromaffin cells were studied with the patch‐clamp technique (Hamill, Marty, Neher, Sakmann & Sigworth… Expand 1. Bovine chromaffin cells were enzymatically isolated and kept in short term tissue culture. Their electrical properties were… Expand Injection of Ca ions increases the membrane permeability of many types of cells (reviewed by Meech1), and in molluscan neurones… Expand This lecture summarizes the knowledge in a field dubbed autopharmacology: the secretion by a body cell of a substance prompted by… Expand