Choline-Phosphate Cytidylyltransferase

Known as: Cytidylyltransferase, CTP Phosphocholine, Phosphorylcholine Cytidyltransferase, CTP, Cytidyltransferase, CTP Phosphorylcholine 
An enzyme that catalyzes the transfer of cytidylate (CMP) to choline phosphate to form CDPcholine. It is the rate-limiting enzyme in the choline… (More)
National Institutes of Health

Related topics

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10 relations
CCT2 geneIn BloodPCYT1A geneProcess of secretion
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Broader (1)

nucleotidyltransferase

Papers overview

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Highly Cited
2005
Highly Cited
2005
Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor gamma ligand.
Nitroalkene derivatives of linoleic acid (nitrolinoleic acid, LNO2) are formed via nitric oxide-dependent oxidative inflammatory… (More)
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Highly Cited
2005
Highly Cited
2005
Strong resistance of phosphorylcholine self-assembled monolayers to protein adsorption: insights into nonfouling properties of zwitterionic materials.
In this work, we show the strong resistance of zwitterionic phosphorylcholine (PC) self-assembled monolayers (SAMs) to protein… (More)
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Highly Cited
2005
Highly Cited
2005
pH-sensitive vesicles based on a biocompatible zwitterionic diblock copolymer.
Highly biocompatible pH-sensitive diblock copolymer vesicles were prepared from the self-assembly of a biocompatible zwitterionic… (More)
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Highly Cited
2004
Highly Cited
2004
Targeted deletion of hepatic CTP:phosphocholine cytidylyltransferase alpha in mice decreases plasma high density and very low density lipoproteins.
CTP:phosphocholine cytidylyltransferase (CT) is the key regulatory enzyme in the CDP-choline pathway for the biosynthesis of… (More)
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Highly Cited
2004
Highly Cited
2004
Surface grafting of artificial joints with a biocompatible polymer for preventing periprosthetic osteolysis.
Periprosthetic osteolysis-bone loss in the vicinity of a prosthesis-is the most serious problem limiting the longevity of… (More)
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Review
2004
Review
2004
Cytidine 5′-Diphosphocholine (CDP-Choline) in Stroke and Other CNS Disorders
Brain phosphatidylcholine (PC) levels are regulated by a balance between synthesis and hydrolysis. Pro-inflammatory cytokines… (More)
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Highly Cited
2002
Highly Cited
2002
Drug susceptibilities of yeast cells are affected by membrane lipid composition.
In the present study we have exploited isogenic erg mutants of Saccharomyces cerevisiae to examine the contribution of an altered… (More)
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Highly Cited
2000
Highly Cited
2000
Modulation of CTP:phosphocholine cytidylyltransferase by membrane curvature elastic stress.
The activity of CTP:phosphocholine cytidylyltransferase, a rate-limiting enzyme in phosphatidylcholine biosynthesis, is modulated… (More)
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Highly Cited
1998
Highly Cited
1998
Why do phospholipid polymers reduce protein adsorption?
The amount of plasma protein adsorbed on a phospholipid polymer having a 2-methacryloyloxyethyl phosphorylcholine (MPC) moiety… (More)
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Highly Cited
1973
Highly Cited
1973
ENDOPLASMIC RETICULUM AS THE SITE OF LECITHIN FORMATION IN CASTOR BEAN ENDOSPERM
The properties of a discrete membranous fraction isolated on sucrose gradients from castor bean endosperm have been examined… (More)
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