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Preparation of Phospholipid Polylners and Their Properties as Polymer Hydrogel Membranes
A methacrylate monomer having the phospholipid polar group, 2-methacryloyloxyethyl phosphorylcholine (MPC) was prepared by an improved method with good yield. MPC was copolymerized with n-butylExpand
Why do phospholipid polymers reduce protein adsorption?
It is concluded that fewer proteins are adsorbed and their original conformation is not changed on polymer surfaces that possess a high free water fraction. Expand
Surface modification on microfluidic devices with 2-methacryloyloxyethyl phosphorylcholine polymers for reducing unfavorable protein adsorption.
It is concluded that the MPC polymers are useful for reducing unfavorable protein adsorption on microfluidic devices. Expand
Biomimetic phosphorylcholine polymer grafting from polydimethylsiloxane surface using photo-induced polymerization.
The surface-modified PDMS is expected to be a novel medical elastomer which possesses an excellent surface hydrophilicity, anti-biofouling property, oxygen permeability and tensile property. Expand
Enhanced solubility of paclitaxel using water-soluble and biocompatible 2-methacryloyloxyethyl phosphorylcholine polymers.
It is concluded that the water-soluble amphiphilic MPC polymers are good solubilizers for PTX as injectable and biocompatible drug formulations. Expand
Protein adsorption from human plasma is reduced on phospholipid polymers.
It is concluded that the reduction of protein adsorption at the blood contacting surface of phospholipid polymers may result in the inhibition of thrombus formation. Expand
Surface grafting of artificial joints with a biocompatible polymer for preventing periprosthetic osteolysis
This approach will make a major improvement in artificial joints by preventing periprosthetic osteolysis and being biologically inert by culture systems with respect to phagocytosis and resorptive cytokine secretion by macrophages. Expand
Preparation of 2-Methacryloyloxyethyl Phosphorylcholine Copolymers with Alkyl Methacrylates and Their Blood Compatibility
Copolymers having the phospholipid polar group, 2-methacryloyloxyethyl phosphorylcholine (MPC) and alkyl methacrylates (n-butyl, tert-butyl, n-hexyl, n-dodecyl, and n-stearyl groups) wereExpand
Adhesion and cytokine production by monocytes on poly(2-methacryloyloxyethyl phosphorylcholine-co-alkyl methacrylate)-coated polymers.
Overall, MPC copolymer-coated and uncoated poly(BMA) were the least stimulating, while TCPS was the most stimulating. Expand
Bone morphogenetic protein encapsulated with a biodegradable and biocompatible polymer.
It is demonstrated that encapsulation of BMP with PLGA could be a promising method to induce bone in clinics because of the high encapsulation yield and release rate in vitro. Expand