Cholera Toxin

Known as: Enterotoxin CT, Cholera, Toxin, Cholera, Exotoxin, Cholera 
An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L… (More)
National Institutes of Health

Related topics

Related topics

22 relations

Narrower (9)

Ace toxinCholera Toxin Protomer ACholeragenoidProcholeragenoid
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Broader (3)

EnterotoxinsImmunologic AdjuvantsPoisons
In BloodProcess of secretionVibrio InfectionsVibrio cholerae
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Papers overview

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Review
2005
Review
2005
Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin, cholera toxin B subunit and CpG DNA.
Mucosal immunisation may be used both to protect the mucosal surfaces against infections and as a means for immunological… (More)
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Review
2003
Review
2003
The intracellular voyage of cholera toxin: going retro.
Cholera toxin (CT) and related AB(5)-subunit toxins move from the plasma membrane through the trans-Golgi and endoplasmic… (More)
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Highly Cited
2002
Highly Cited
2002
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.
Secretory diarrhea is the leading cause of infant death in developing countries and a major cause of morbidity in adults. The… (More)
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Highly Cited
2001
Highly Cited
2001
Protein Disulfide Isomerase Acts as a Redox-Dependent Chaperone to Unfold Cholera Toxin
Cholera toxin is assembled from two subunits in the periplasm of Vibrio cholerae and disassembled in the analogous compartment of… (More)
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Highly Cited
2001
Highly Cited
2001
Internalization of cholera toxin by different endocytic mechanisms.
The mechanism of cholera toxin (CT) internalization has been investigated using Caco-2 cells transfected with caveolin to induce… (More)
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Highly Cited
1998
Highly Cited
1998
Filipin-dependent Inhibition of Cholera Toxin: Evidence for Toxin Internalization and Activation through Caveolae-like Domains
The mechanism by which cholera toxin (CT) is internalized from the plasma membrane before its intracellular reduction and… (More)
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Highly Cited
1998
Highly Cited
1998
Skin immunization made possible by cholera toxin
Immunization using an application to the skin surface, without physical penetration by needles, would greatly increase the ease… (More)
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Highly Cited
1996
Highly Cited
1996
Lysogenic conversion by a filamentous phage encoding cholera toxin.
Vibrio cholerae, the causative agent of cholera, requires two coordinately regulated factors for full virulence: cholera toxin… (More)
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Review
1992
Review
1992
Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin.
Cholera and the related Escherichia coli-associated diarrheal disease are important problems confronting Third World nations and… (More)
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Highly Cited
1987
Highly Cited
1987
Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein
The toxR gene encodes a transcriptional activator controlling cholera toxin, pilus, and outer-membrane protein expression in V… (More)
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