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Cholera Toxin

Known as: Enterotoxin CT, Cholera, Toxin, Cholera, Exotoxin, Cholera 
An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L… 
National Institutes of Health

Related topics

Related topics

23 relations

Narrower (10)

Ace toxinCholera Toxin Protomer ACholeragenoidProcholeragenoid
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Broader (3)

EnterotoxinsImmunologic AdjuvantsPoisons
In BloodProcess of secretionVibrio InfectionsVibrio cholerae
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Multiplexed toxin analysis using four colors of quantum dot fluororeagents.
Quantum dots (QDs) have the potential to simplify the performance of multiplexed analysis. In this work, we prepared bioinorganic… 
Highly Cited
2002
Highly Cited
2002
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.
Secretory diarrhea is the leading cause of infant death in developing countries and a major cause of morbidity in adults. The… 
Highly Cited
2001
Highly Cited
2001
Internalization of cholera toxin by different endocytic mechanisms.
The mechanism of cholera toxin (CT) internalization has been investigated using Caco-2 cells transfected with caveolin to induce… 
Highly Cited
1998
Highly Cited
1998
Filipin-dependent Inhibition of Cholera Toxin: Evidence for Toxin Internalization and Activation through Caveolae-like Domains
The mechanism by which cholera toxin (CT) is internalized from the plasma membrane before its intracellular reduction and… 
Highly Cited
1996
Highly Cited
1996
Lysogenic Conversion by a Filamentous Phage Encoding Cholera Toxin
Vibrio cholerae, the causative agent of cholera, requires two coordinately regulated factors for full virulence: cholera toxin… 
Highly Cited
1994
Highly Cited
1994
Crystal structure of cholera toxin B‐pentamer bound to receptor GM1 pentasaccharide
Cholera toxin (CT) is an AB5 hexameric protein responsible for the symptoms produced by Vibrio cholerae infection. In the first… 
Review
1992
Review
1992
Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin.
  • B. Spangler
  • Microbiological reviews
  • 1992
  • Corpus ID: 22751945
Cholera and the related Escherichia coli-associated diarrheal disease are important problems confronting Third World nations and… 
Highly Cited
1982
Highly Cited
1982
Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin.
Cultures consisting almost entirely of human melanocytes were obtained from epidermal single-cell suspensions by using phorbol 12… 
Highly Cited
1978
Highly Cited
1978
Mechanism of cholera toxin action: covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system.
Treatment of pigeon erythrocyte membranes with cholera toxin and NAD(+) enhanced the GTP stimulation and suppressed the F… 
Highly Cited
1978
Highly Cited
1978
ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase.
  • D. Gill, R. Meren
  • Proceedings of the National Academy of Sciences…
  • 1978
  • Corpus ID: 25453003
In the presence of ATP and a cytosolic factor, cholera toxin fragment A1 catalyzes the transfer of ADP-ribose from NAD to a… 
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