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Cholera Toxin

Known as: Enterotoxin CT, Cholera, Toxin, Cholera, Exotoxin, Cholera 
An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L… 
National Institutes of Health

Related topics

Related topics

23 relations

Narrower (10)

Ace toxinCholera Toxin Protomer ACholeragenoidProcholeragenoid

Broader (3)

EnterotoxinsImmunologic AdjuvantsPoisons
In BloodProcess of secretionVibrio InfectionsVibrio cholerae

Papers overview

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Highly Cited
2006
Highly Cited
2006
Electrochemical immunosensor for cholera toxin using liposomes and poly(3,4-ethylenedioxythiophene)-coated carbon nanotubes.
A sensitive method for the detection of cholera toxin (CT) using an electrochemical immunosensor with liposomic magnification… 
Review
2004
Review
2004
Cholera toxin: A paradigm for multi-functional engagement of cellular mechanisms (Review)
Cholera toxin (Ctx) from Vibrio cholerae and its closely related homologue, heat-labile enterotoxin (Etx) from Escherichia coli… 
Highly Cited
1998
Highly Cited
1998
Skin immunization made possible by cholera toxin
Immunization using an application to the skin surface, without physical penetration by needles, would greatly increase the ease… 
Highly Cited
1995
Highly Cited
1995
The three-dimensional crystal structure of cholera toxin.
The clinical manifestations of cholera are largely attributable to the actions of a secreted hexameric AB5 enterotoxin… 
Highly Cited
1995
Highly Cited
1995
Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4.
Despite pathophysiologic effects including diarrhea, cholera toxin (CT) is a potent mucosal immunogen and adjuvant. We… 
Highly Cited
1993
Highly Cited
1993
Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues
Antigen-specific B cell responses to mucosally delivered proteins are dependent upon CD4-positive T helper (Th) cells, and the… 
Highly Cited
1984
Highly Cited
1984
Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin.
Cholera toxin (CT) has been found to be an extremely potent immunogen for mucosal IgA responses when administered via the… 
Highly Cited
1984
Highly Cited
1984
Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin.
A factor (ARF) that is required for the cholera toxin-dependent ADP-ribosylation of the stimulatory, GTP-binding regulatory… 
Highly Cited
1982
Highly Cited
1982
Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin.
Cultures consisting almost entirely of human melanocytes were obtained from epidermal single-cell suspensions by using phorbol 12… 
Highly Cited
1980
Highly Cited
1980
Amino acid sequence homology between cholera toxin and Escherichia coli heat-labile toxin
Cholera toxin (CT) and the Escherichia coli heat-labile toxin (LT) are functionally, structurally and immunologically similar… 
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