Chemokine CXCL12

Known as: CXCL12, Chemokine, PBSF, Stromal Cell-Derived Factor 1 
A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Chemokines, small proinflammatory chemoattractant cytokines that bind to specific G-protein-coupled seven-span transmembrane… (More)
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Highly Cited
2009
Highly Cited
2009
Apoptosis is a pivotal process in embryogenesis and postnatal cell homeostasis and involves the shedding of membranous… (More)
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Review
2008
Review
2008
Chemotactic cytokines (chemokines) have been traditionally defined as small (10-14kDa) secreted leukocyte chemoattractants… (More)
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Highly Cited
2006
Highly Cited
2006
In the bone marrow, the special microenvironment niches nurture a pool of hematopoietic stem cells (HSCs). Many HSCs reside near… (More)
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Highly Cited
2005
Highly Cited
2005
Fibroblasts often constitute the majority of the stromal cells within a breast carcinoma, yet the functional contributions of… (More)
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Highly Cited
2005
Highly Cited
2005
Combined phylogenetic and chromosomal location studies suggest that the orphan receptor RDC1 is related to CXC chemokine… (More)
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Highly Cited
2002
Highly Cited
2002
Of 14 chemokine receptors investigated, only CXCR4 was expressed on ovarian cancer cells [C. J. Scotton et al., Cancer Res., 61… (More)
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Highly Cited
2000
Highly Cited
2000
Leukocyte traffic through secondary lymphoid tissues is finely tuned by chemokines. We have studied the functional properties of… (More)
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Highly Cited
1998
Highly Cited
1998
Vascularization of organs generally occurs by remodelling of the preexisting vascular system during their differentiation and… (More)
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Highly Cited
1996
Highly Cited
1996
THE chemokines are a large family of small, structurally related cytokines1,2. The physiological importance of most members of… (More)
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