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Chemokine CXCL12

Known as: CXCL12, Chemokine, PBSF, Stromal Cell-Derived Factor 1 
A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (7)

CTCE-0214CXCL12 protein, humanSDF1-3'AStromal Cell-Derived Factor-1alpha
CXCL12 geneCXCL12 wt AlleleIn BloodProcess of secretion

Broader (2)

chemokinecytokine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
The pivotal role of CXCL12 (SDF-1)/CXCR4 axis in bone metastasis
Tumor cells are known to adapt to and utilize existing physiological mechanisms to promote survival and metastasis. The role of… 
Highly Cited
2007
Highly Cited
2007
Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction.
AIM The recently published REPAIR-AMI and ASTAMI trial showed differences in contractile recovery of left ventricular function… 
Highly Cited
2007
Highly Cited
2007
Towards in situ tissue repair: Human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2
The recruitment of bone marrow CD34− mesenchymal stem‐ and progenitor cells (MSC) and their subsequent differentiation into… 
Highly Cited
2006
Highly Cited
2006
Low-Energy Shock Wave for Enhancing Recruitment of Endothelial Progenitor Cells: A New Modality to Increase Efficacy of Cell Therapy in Chronic Hind Limb Ischemia
Background— Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of ischemic tissue… 
Highly Cited
2004
Highly Cited
2004
Inflammation Controls B Lymphopoiesis by Regulating Chemokine CXCL12 Expression
Inflammation removes developing and mature lymphocytes from the bone marrow (BM) and induces the appearance of developing B cells… 
Highly Cited
2000
Highly Cited
2000
Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma.
Glioblastoma multiforme (GBM) tumors display extensive histomorphological heterogeneity, with great variability in the extent of… 
Highly Cited
1997
Highly Cited
1997
A Small Molecule CXCR4 Inhibitor that Blocks T Cell Line–tropic HIV-1 Infection
Several members of the chemokine receptor family have been shown to function in association with CD4 to permit human… 
Highly Cited
1997
Highly Cited
1997
CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons
Highly Cited
1996
Highly Cited
1996
Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor…
Pre-B-cell growth-stimulating factor/ stromal cell-derived factor 1 (PBSF/SDF-1) is a member of the CXC group of chemokines that… 
Highly Cited
1995
Highly Cited
1995
Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene.
Stromal cell-derived factors 1 alpha and 1 beta are small cytokines belonging to the intercrine CXC subfamily and originally… 
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