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Stromal Cell-Derived Factor-1alpha

Known as: SDF 1alpha, SDF-1alpha, Stromal Cell Derived Factor 1alpha 
National Institutes of Health

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Related topics

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Broader (1)

Chemokine CXCL12

Papers overview

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Highly Cited
2008
Highly Cited
2008
Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: one plausible explanation of Scherer's structures.
The morphological patterns of glioma cell invasion are known as the secondary structures of Scherer. In this report, we propose a… 
Highly Cited
2004
Highly Cited
2004
Involvement of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1alpha in breast cancer cell migration through human brain microvascular endothelial cells.
In this study, we have characterized the signaling pathways mediated by CXCR4 in breast cancer cells and its role in breast… 
Highly Cited
2003
Highly Cited
2003
Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt.
In this paper, we describe the role of chemokine receptor CXCR4 activation by its natural ligand, the chemokine stromal cell… 
Highly Cited
2003
Highly Cited
2003
Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence.
Highly Cited
2002
Highly Cited
2002
A Dual Role for the SDF-1/CXCR4 Chemokine Receptor System in Adult Brain: Isoform-Selective Regulation of SDF-1 Expression Modulates CXCR4-Dependent Neuronal Plasticity and Cerebral Leukocyte…
The chemoattractant stromal cell-derived factor-1 (SDF-1) and its receptor CXC chemokine receptor 4 (CXCR4) are key modulators of… 
Highly Cited
2001
Highly Cited
2001
Matrix Metalloproteinase Activity Inactivates the CXC Chemokine Stromal Cell-derived Factor-1*
Chemokines provide directional cues for leukocyte migration and activation that are essential for normal leukocytic trafficking… 
Highly Cited
2001
Highly Cited
2001
Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization
Redistribution of specialized molecules in migrating cells develops asymmetry between two opposite cell poles, the leading edge… 
Highly Cited
1999
Highly Cited
1999
Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells.
Chemokines play a central role for lymphocyte trafficking and homing. The mechanisms that direct the tissue localization of B… 
Highly Cited
1998
Highly Cited
1998
The α-Chemokine, Stromal Cell-derived Factor-1α, Binds to the Transmembrane G-protein-coupled CXCR-4 Receptor and Activates Multiple Signal Transduction Pathways*
The α-chemokine stromal cell-derived factor (SDF)-1α binds to the seven transmembrane G-protein-coupled CXCR-4 receptor and acts… 
Highly Cited
1997
Highly Cited
1997
HIV Coreceptor Downregulation as Antiviral Principle: SDF-1α–dependent Internalization of the Chemokine Receptor CXCR4 Contributes to Inhibition of HIV Replication
Ligation of CCR5 by the CC chemokines RANTES, MIP-1α or MIP-1β, and of CXCR4 by the CXC chemokine SDF-1α, profoundly inhibits the… 
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