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Chemokine (C-C Motif) Receptor 5

Known as: CKR5 Receptors, Receptors, CCR5, Antigens, CD195 
CCR receptors with specificity for CHEMOKINE CCL3; CHEMOKINE CCL4; and CHEMOKINE CCL5. They are expressed at high levels in T-LYMPHOCYTES; B… 
National Institutes of Health

Related topics

Related topics

8 relations
CCR5 geneIn Bloodagonistsaspects of radiation effects

Narrower (2)

CCR5 protein, humanCCR5 receptor (222-240)

Broader (1)

Receptors, Cytokine

Papers overview

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Highly Cited
2010
Highly Cited
2010
Cardiovascular , Pulmonary and Renal Pathology CCR 5 Signaling Suppresses Inflammation and Reduces Adverse Remodeling of the Infarcted Heart , Mediating Recruitment of Regulatory T Cells
Myocardial infarction triggers an inflammatory reaction that is involved in cardiac remodeling. Cardiac repair is dependent on… 
2009
2009
Chemokine receptor Ccr5 deficiency induces alternative macrophage activation and improves long‐term renal allograft outcome
The chemokine (C‐C motif) receptor 5 (CCR5) has been implicated in experimental and clinical allograft rejection. To dissect the… 
Highly Cited
2008
Highly Cited
2008
Fluorescence Resonance Energy Transfer Imaging Reveals that Chemokine-Binding Modulates Heterodimers of CXCR4 and CCR5 Receptors
Background Dimerization has emerged as an important feature of chemokine G-protein-coupled receptors. CXCR4 and CCR5 regulate… 
Highly Cited
2004
Highly Cited
2004
R5 HIV gp120‐mediated cellular contacts induce the death of single CCR5‐expressing CD4 T cells by a gp41‐dependent mechanism
The use of CXC chemokine receptor 4 (CXCR4) and CC chemokine receptor 5 (CCR5) by X4 and R5 human immunodeficiency virus (HIV… 
Highly Cited
2002
Highly Cited
2002
Alcohol potentiates HIV-1 infection of human blood mononuclear phagocytes.
BACKGROUND Acute and chronic alcohol abuse impairs various functions of the immune system and thus has been implicated as a… 
Highly Cited
2000
Highly Cited
2000
Macrophages infiltrating the tissue in chronic pancreatitis express the chemokine receptor CCR5.
BACKGROUND The immunologic mechanisms involved in the development of chronic pancreatitis (CP) are poorly understood. Chronically… 
Highly Cited
1999
Highly Cited
1999
Analysis of the Critical Domain in the V3 Loop of Human Immunodeficiency Virus Type 1 gp120 Involved in CCR5 Utilization
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) infection of CD4+ lymphocytes and macrophages involves interaction of the… 
Review
1999
Review
1999
Chemokine‐induced phosphorylation of CC chemokine receptor 5 (CCR5)
The CC‐chemokine receptor 5 (CCR5) mediates activation of T lymphocytes and macrophages by chemokines and is a major co‐receptor… 
Highly Cited
1998
Highly Cited
1998
Early activation of mitogen-activated protein kinase kinase, extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and c-Jun N-terminal kinase in response to binding of simian…
We have shown that the binding of simian immunodeficiency virus (SIV) to Jurkat T cells expressing CD4 receptor strongly induces… 
Highly Cited
1998
Highly Cited
1998
Gene organization and promoter function for CC chemokine receptor 5 (CCR5).
CC chemokine receptor 5 (CCR5) functions physiologically as a receptor for the leukocyte chemoattractants macrophage inflammatory… 
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