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Chemokine (C-C Motif) Receptor 5

Known as: CKR5 Receptors, Receptors, CCR5, Antigens, CD195 
CCR receptors with specificity for CHEMOKINE CCL3; CHEMOKINE CCL4; and CHEMOKINE CCL5. They are expressed at high levels in T-LYMPHOCYTES; B… Expand
National Institutes of Health

Related topics

Related topics

8 relations
CCR5 geneIn Bloodagonistsaspects of radiation effects
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Narrower (2)

CCR5 protein, humanCCR5 receptor (222-240)

Broader (1)

Receptors, Cytokine

Papers overview

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Highly Cited
2009
Highly Cited
2009
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
Neutralizing antibodies are thought to be crucial for HIV vaccine protection, but studies in animal models suggest that high… Expand
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Highly Cited
2008
Highly Cited
2008
Subgroup analyses of maraviroc in previously treated R5 HIV-1 infection.
BACKGROUND We conducted subanalyses of the combined results of the Maraviroc versus Optimized Therapy in Viremic Antiretroviral… Expand
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Highly Cited
2005
Highly Cited
2005
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus–cell fusion
Human immunodeficiency virus type 1 (HIV-1) continues to spread, principally by heterosexual sex, but no vaccine is available… Expand
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Highly Cited
2004
Highly Cited
2004
HIV-1 Cell to Cell Transfer across an Env-induced, Actin-dependent Synapse
Direct cell–cell transfer is an efficient mechanism of viral dissemination within an infected host, and human immunodeficiency… Expand
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Highly Cited
2001
Highly Cited
2001
CC chemokine receptor 5 and renal-transplant survival
BACKGROUND About 1% of white populations are homozygous carriers of an allele of the gene for the CC chemokine receptor 5 (CCR5… Expand
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Highly Cited
1998
Highly Cited
1998
CCR5 is characteristic of Th1 lymphocytes
CD4+ lymphocytes can be assigned to two subsets. Th1 lymphocytes secrete interferon gamma (IFNγ) and lymphotoxin, promoting cell… Expand
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Highly Cited
1997
Highly Cited
1997
CCR5 Levels and Expression Pattern Correlate with Infectability by Macrophage-tropic HIV-1, In Vitro
Chemokine receptors serve as coreceptors for HIV entry into CD4+ cells. Their expression is thought to determine the tropism of… Expand
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Highly Cited
1997
Highly Cited
1997
Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines.
Dendritic cells (DC) are migratory cells that exhibit complex trafficking properties in vivo. The present study was designed to… Expand
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Highly Cited
1997
Highly Cited
1997
Regulation of the Receptor Specificity and Function of the Chemokine RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted) by Dipeptidyl Peptidase IV (CD26)-mediated Cleavage
CD26 is a leukocyte activation marker that possesses dipeptidyl peptidase IV activity but whose natural substrates and… Expand
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Highly Cited
1996
Highly Cited
1996
Molecular cloning and functional expression of a new human CC-chemokine receptor gene.
The cloning of several receptors activated by either CC or CXC chemokines and belonging to the G protein-coupled family of… Expand
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