Chemokine (C-C Motif) Receptor 5

Known as: CKR5 Receptors, Receptors, CCR5, Antigens, CD195 
CCR receptors with specificity for CHEMOKINE CCL3; CHEMOKINE CCL4; and CHEMOKINE CCL5. They are expressed at high levels in T-LYMPHOCYTES; B… (More)
National Institutes of Health

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CCR5 geneIn Bloodagonistsaspects of radiation effects
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Narrower (1)

CCR5 protein, human

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Receptors, Cytokine

Papers overview

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Highly Cited
2010
Highly Cited
2010
Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis…
UNLABELLED Patients coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) develop more rapid fibrosis… (More)
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Highly Cited
2009
Highly Cited
2009
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
Neutralizing antibodies are thought to be crucial for HIV vaccine protection, but studies in animal models suggest that high… (More)
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2008
2008
Chemokine (C-C motif) receptor 5-using envelopes predominate in dual/mixed-tropic HIV from the plasma of drug-naive individuals.
OBJECTIVE HIV-1 utilizes CD4 and either chemokine (C-C motif) receptor 5 (CCR5) or chemokine (C-X-C motif) receptor 4 (CXCR4) to… (More)
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Highly Cited
2005
Highly Cited
2005
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus–cell fusion
Human immunodeficiency virus type 1 (HIV-1) continues to spread, principally by heterosexual sex, but no vaccine is available… (More)
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2002
2002
Beta-arrestin binding to CC chemokine receptor 5 requires multiple C-terminal receptor phosphorylation sites and involves a conserved Asp-Arg-Tyr sequence motif.
Agonist binding to the CC chemokine receptor 5 (CCR5) induces the phosphorylation of four distinct serine residues that are… (More)
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Highly Cited
2001
Highly Cited
2001
CC chemokine receptor 5 and renal-transplant survival
BACKGROUND About 1% of white populations are homozygous carriers of an allele of the gene for the CC chemokine receptor 5 (CCR5… (More)
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Highly Cited
1997
Highly Cited
1997
Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: studies in populations with contrasting clinical phenotypes, defined racial background, and quantified…
BACKGROUND CC chemokine receptor 5 (CCR5) is a cell entry cofactor for macrophage-tropic isolates of human immunodeficiency virus… (More)
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Highly Cited
1997
Highly Cited
1997
CCR5 Levels and Expression Pattern Correlate with Infectability by Macrophage-tropic HIV-1, In Vitro
Chemokine receptors serve as coreceptors for HIV entry into CD4+ cells. Their expression is thought to determine the tropism of… (More)
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Highly Cited
1997
Highly Cited
1997
Regulation of the Receptor Specificity and Function of the Chemokine RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted) by Dipeptidyl Peptidase IV (CD26)-mediated Cleavage
CD26 is a leukocyte activation marker that possesses dipeptidyl peptidase IV activity but whose natural substrates and… (More)
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Highly Cited
1996
Highly Cited
1996
Molecular cloning and functional expression of a new human CC-chemokine receptor gene.
The cloning of several receptors activated by either CC or CXC chemokines and belonging to the G protein-coupled family of… (More)
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