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Central Nervous System Sensitization

Known as: Sensitization, Central, Central Sensitization, Sensitizations, Central 
An increased response to stimulation that is mediated by amplification of signaling in the CENTRAL NERVOUS SYSTEM (CNS).
National Institutes of Health

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2 relations
aspects of radiation effectsphysiological aspects

Papers overview

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Review
2015
Review
2015
Drug targets of migraine and neuropathy: treatment of hyperexcitability.
Migraine and neuropathic pain are common causes of chronic pain. The exact pathomechanism has not been fully clarified for either… 
2012
2012
Spatial pain propagation over time following painful glutamate activation of latent myofascial trigger points in humans.
Review
2010
Review
2010
Central neuron-glia interactions and neuropathic pain
GLOSSARYAMPA = &agr;-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; ATP = adenosine triphosphate; BDNF = brain-derived… 
2010
2010
Synaptic plasticity and central sensitization: author reply.
2010
2010
Central sensitization does not identify patients with carpal tunnel syndrome who are likely to achieve short-term success with physical therapy
The aim of the current study was to identify whether hyperexcitability of the central nervous system is a prognostic factor for… 
2006
2006
Centralization, central sensitization and neuropathic pain. Focus on "sciatic chronic constriction injury produces cell-type-specific changes in the electrophysiological properties of rat substantia…
Admiral Lord Nelson lost his right arm in a sea battle some years before his successful encounter with the forces of Napoleon at… 
2005
2005
Abrupt Onset and Termination of Cutaneous Allodynia (Central Sensitization) During Attacks of SUNCT
The presence of central sensitization and cutaneous allodynia has not been readily studied in other primary headache syndromes… 
Review
2004
Review
2004
Visceral hypersensitivity in noncardiac chest pain.
2003
2003
Reduced spinal cord sensitization to C‐fibre stimulation in mice over‐expressing galanin
The neuropeptide galanin may have a role in spinal nociception. In this study, we examined the excitability of the flexor reflex… 
Highly Cited
1999
Highly Cited
1999
Adenosine reduces secondary hyperalgesia in two human models of cutaneous inflammatory pain.
UNLABELLED Secondary hyperalgesia is characterized by increased sensitivity to noxious mechanical stimuli in the area surrounding… 
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