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Cefmetazole

Known as: Cefmetazolo, (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((cyanomethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-cis)- 
A second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefmetazole binds to penicillin-binding… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (2)

Anti-Bacterial AgentsCephamycins

Narrower (3)

CS-1170CefmetazonZefazone
Cefmetazole SodiumIn Bloodagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Long-term changes of gut microbiota, antibiotic resistance, and metabolic parameters after Helicobacter pylori eradication: a multicentre, open-label, randomised trial.
Highly Cited
2015
Highly Cited
2015
Multicenter Retrospective Study of Cefmetazole and Flomoxef for Treatment of Extended-Spectrum-β-Lactamase-Producing Escherichia coli Bacteremia
ABSTRACT The efficacy of cefmetazole and flomoxef (CF) for the treatment of patients with extended-spectrum β-lactamase-producing… 
Highly Cited
2011
Highly Cited
2011
Simultaneous determination of eight β-lactam antibiotics in human serum by liquid chromatography-tandem mass spectrometry.
Review
2008
Review
2008
Chimeric mice with humanized liver.
Highly Cited
2002
Highly Cited
2002
Investigation of extended-spectrum beta-lactamase in Klebsiellae pneumoniae and Escherichia coli from China.
Highly Cited
1992
Highly Cited
1992
Guidelines for clinical care: anti-infective agents for intra-abdominal infection. A Surgical Infection Society policy statement.
Several antibiotics have been marketed for therapeutic use in intra-abdominal infection. Often, these agents do not provide a… 
Highly Cited
1990
Highly Cited
1990
Novel plasmid-mediated beta-lactamase (MIR-1) conferring resistance to oxyimino- and alpha-methoxy beta-lactams in clinical isolates of Klebsiella pneumoniae
Klebsiella pneumoniae isolates from 11 patients at the Miriam Hospital were identified as resistant to cefoxitin and ceftibuten… 
Highly Cited
1986
Highly Cited
1986
Peptidoglycan synthetic activities in membranes of Escherichia coli caused by overproduction of penicillin-binding protein 2 and rodA protein.
Highly Cited
1986
Highly Cited
1986
Antibacterial activity of cefmetazole alone and in combination with fosfomycin against methicillin- and cephem-resistant Staphylococcus aureus
In vitro and in vivo antibacterial activities of cefmetazole alone and in combination with fosfomycin against methicillin- and… 
Highly Cited
1982
Highly Cited
1982
A mecillinam-sensitive peptidoglycan crosslinking reaction in Escherichia coli.
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