Cathepsin E

Known as: Cathepsin E [Chemical/Ingredient], Moving Proteinase, Slow, Slow Moving Proteinase 
An aspartic endopeptidase that is similar in structure to CATHEPSIN D. It is found primarily in the cells of the immune system where it may play a… (More)
National Institutes of Health

Related topics

Related topics

11 relations

Broader (2)

Aspartic Acid EndopeptidasesCathepsins
CTSE geneIn BloodProcess of secretionantagonists & inhibitors
(More)

Narrower (1)

procathepsin E

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Cathepsin E, maspin, Plk1, and survivin are promising prognostic protein markers for progression in non-muscle invasive bladder cancer.
Bladder cancer is a common cancer with particularly high recurrence after transurethral resection. In this study, we investigated… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
Is this relevant?
2012
2012
Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models.
BACKGROUND AND AIMS Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in the USA. Surgical… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2007
2007
Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface.
The aspartic proteinase cathepsin E is expressed predominantly in cells of the immune system and highly secreted by activated… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2007
2007
Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E.
The aspartic proteinase cathepsin E is localized mainly in the endosomal structures of APCs and has been implicated in a variety… (More)
Is this relevant?
2006
2006
Cathepsin D-mediated proteolysis of apolipoprotein E: Possible role in Alzheimer’s disease
Proteolysis of apolipoprotein E (apoE) may be involved in the pathogenesis of Alzheimer's disease (AD). We previously identified… (More)
Is this relevant?
2004
2004
Cathepsin D, but not cathepsin E, degrades desmosomes during epidermal desquamation.
BACKGROUND We previously reported that an ambient aspartic proteinase is crucial to desquamation of the stratum corneum at pH 5… (More)
Is this relevant?
2003
2003
Association of cathepsin E deficiency with development of atopic dermatitis.
Atopic dermatitis (AD) is a pruritic inflammatory skin diseases associated with a family history of atropy. Here we show that… (More)
Is this relevant?
1998
1998
Identification of cellular compartments involved in processing of cathepsin E in primary cultures of rat microglia.
Cathepsin E is a major nonlysosomal, intracellular aspartic proteinase that localizes in various cellular compartments such as… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1993
1993
Cathepsin E in follicle associated epithelium of intestine and tonsils: localization to M cells and possible role in antigen processing
A specific rabbit anti-human serum was used selectively to localize the aspartic proteinase cathepsin E to follicle associated… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E.
Proteolytic degradation (processing) of antigen by antigen-presenting cells is a major regulatory step in the activation of a T… (More)
Is this relevant?