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Carnitine palmitoyl transferase 1A deficiency

Known as: CPT 1A Deficiency, CPT Deficiency, Hepatic, Type I, Carnitine palmitoyltransferase 1 deficiency 
A rare autosomal recessive inherited disorder caused by mutations in the CPT1A gene. It is characterized by the presence of defective carnitine… 
National Institutes of Health

Related topics

Related topics

16 relations
Autosomal recessive inheritanceCPT1A geneComatoseConditions tested for in this newborn screening study:ID:Pt:Bld.dot:Nom

Broader (3)

Carnitine O-PalmitoyltransferaseHypoglycemiaLipid Metabolism, Inborn Errors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Spiritually Integrated Cognitive Processing Therapy: A New Treatment for Post-traumatic Stress Disorder That Targets Moral Injury
Background Post-traumatic stress disorder (PTSD) is a debilitating disorder, and current treatments leave the majority of… 
Highly Cited
2014
Highly Cited
2014
Crude Extracts from Lycium barbarum Suppress SREBP-1c Expression and Prevent Diet-Induced Fatty Liver through AMPK Activation
Lycium barbarum polysaccharide (LBP) is well known in traditional Chinese herbal medicine that, has beneficial effects. Previous… 
Highly Cited
2013
Highly Cited
2013
Endophytic fungi from Miquelia dentata Bedd., produce the anti-cancer alkaloid, camptothecine.
Highly Cited
2010
Highly Cited
2010
Compensatory Increases in Nuclear PGC1α Protein Are Primarily Associated With Subsarcolemmal Mitochondrial Adaptations in ZDF Rats
OBJECTIVE We examined in insulin-resistant muscle if, in contrast to long-standing dogma, mitochondrial fatty acid oxidation is… 
Highly Cited
2008
Highly Cited
2008
Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria
Peroxisome proliferator‐activated receptors (PPARs) alter the expression of genes involved in regulating lipid metabolism… 
Highly Cited
2005
Highly Cited
2005
Human Multidrug Resistance Associated Protein 4 Confers Resistance to Camptothecins
PurposeThe multidrug resistance associated protein (MRP) 4 is a member of the adenosine triphosphate (ATP)-binding cassette… 
Highly Cited
2005
Highly Cited
2005
Malonyl-CoA decarboxylase inhibition suppresses fatty acid oxidation and reduces lactate production during demand-induced ischemia.
The rate of cardiac fatty acid oxidation is regulated by the activity of carnitine palmitoyltransferase-I (CPT-I), which is… 
2005
2005
Serious pregnancy complications in a patient with previously undiagnosed carnitine palmitoyltransferase 1 deficiency.
Highly Cited
2004
Highly Cited
2004
Chronic C75 treatment of diet-induced obese mice increases fat oxidation and reduces food intake to reduce adipose mass.
Obesity and its attendant disorders, such as type 2 diabetes, are global health problems. We previously reported that C75, an… 
1985
1985
Inhibition of Mitochondrial Carnitine Palmitoyl Transferase A in Vivo with Methyl 2-Tetradecylglycidate (Methyl Palmoxirate) and Its Relationship to Ketonemia and Glycemia 1
Abstract The oral hypoglycemic agent, methyl 2-tetradecylglycidate (Me-TDGA), which inhibits in vitro mitochondrial carnitine… 
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