Carnitine O-Palmitoyltransferase

This review summarizes how fatty acid (FA) oxidation is regulated in skeletal muscle during exercise. From the available evidence… Expand

Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are active players in the formation of… Expand

We previously showed gut microbial production of trimethylamine N -oxide (TMAO) from dietary nutrients like choline, lecithin… Expand

Intestinal microbiota metabolism of choline and phosphatidylcholine produces trimethylamine (TMA), which is further metabolized… Expand

Previous studies have suggested that insulin resistance develops secondary to diminished fat oxidation and resultant accumulation… Expand

Adiponectin has recently been shown to be a promising candidate for the treatment of obesity-associated metabolic syndromes… Expand

We measured production of reactive oxygen species by intact mitochondria from rat skeletal muscle, heart, and liver under various… Expand

We argue for the critical role of oxidative damage in causing the mitochondrial dysfunction of aging. Oxidants generated by… Expand

Carnitine was detected at the beginning of this century, but it was nearly forgotten among biochemists until its importance in… Expand

1. Pigeon heart mitochondria produce H(2)O(2) at a maximal rate of about 20nmol/min per mg of protein. 2. Succinate-glutamate and… Expand