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Probiotic bacteria enhance murine and human intestinal epithelial barrier function.
BACKGROUND & AIMS The probiotic compound, VSL#3, is efficacious as maintenance therapy in pouchitis and ulcerative colitis. The aim of this study was to determine the efficacy of VSL#3 as a primary… Expand
Beneficial Effects of a Probiotic VSL#3 on Parameters of Liver Dysfunction in Chronic Liver Diseases
- C. Loguercio, A. Federico, +4 authors C. D. Blanco
- Journal of clinical gastroenterology
- 1 July 2005
Objectives: To evaluate whether chronic therapy with probiotics affects plasma levels of cytokines and oxidative/nitrosative stress parameters, as well as liver damage, in patients with various types… Expand
DNA from probiotic bacteria modulates murine and human epithelial and immune function.
BACKGROUND & AIMS The intestinal epithelium must discriminate between pathogenic and nonpathogenic bacteria and respond accordingly. The aim of this study was to examine whether bacterial DNA can… Expand
Probiotics inhibit nuclear factor-kappaB and induce heat shock proteins in colonic epithelial cells through proteasome inhibition.
BACKGROUND AND AIMS The extent and severity of mucosal injury in inflammatory bowel diseases are determined by the disequilibrium between 2 opposing processes: reparative and cytoprotective… Expand
The VSL#3 probiotic formula induces mucin gene expression and secretion in colonic epithelial cells.
- C. Caballero-Franco, K. Keller, C. De Simone, K. Chadee
- Biology, Medicine
- American journal of physiology. Gastrointestinal…
Several studies have stressed the importance of the microbiota in the maintenance of the gastrointestinal epithelium. Administration of probiotic bacteria, supplements composed of microbiota… Expand
Oxygen radicals can induce preconditioning in rabbit hearts.
Indirect evidence suggests that oxygen radicals may contribute to ischemic preconditioning. We directly investigated whether exposure to oxygen radicals per se, in the absence of ischemia, could… Expand
Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration.
BACKGROUND Hyperoxaluria is a major risk factor for renal stones, and in most cases, it appears to be sustained by increased dietary load or increased intestinal absorption. Previous studies have… Expand
Apoptosis and surgical trauma: dysregulated expression of death and survival factors on peripheral lymphocytes.
BACKGROUND Surgery and anesthesia cause depression of cell-mediated immunity in the postoperative period, including a reduction in the numbers of circulating lymphocytes. It has been claimed that… Expand
VSL#3 probiotic preparation has the capacity to hydrolyze gliadin polypeptides responsible for Celiac Sprue.
- M. De Angelis, C. G. Rizzello, +6 authors M. Gobbetti
- Chemistry, Medicine
- Biochimica et biophysica acta
The native structure and distribution of gliadin epitopes responsible for Celiac Sprue (CS) may be influenced by cereal food processing. This work was aimed at showing the capacity of probiotic VSL#3… Expand
Use of a probiotic to decrease enteric hyperoxaluria.
BACKGROUND Patients with inflammatory bowel disease have a 10- to 100-fold increased risk of nephrolithiasis, with enteric hyperoxaluria being the major risk factor for these and other patients with… Expand