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Salivary phosphate-binding chewing gum reduces hyperphosphatemia in dialysis patients.
In uremic patients, hyperphosphatemia is associated with cardiovascular calcification and increased cardiovascular mortality. Despite the use of phosphate binders, only half of hemodialysis (HD)Expand
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Correlation between increased serum and tissue L-carnitine levels and improved muscle symptoms in hemodialyzed patients.
A group of 14 uremic patients on intermittent hemodialysis was admitted to a cross-over double-blind trial in order to evaluate serum and muscle carnitine levels before and after 60 days ofExpand
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Carnitine: An osmolyte that plays a metabolic role
Carnitine, gamma‐trimethyl‐beta‐hydroxybutyrobetaine, is a small molecule widely present in all cells from prokaryotic to eukaryotic ones. It is the sole source of carbon and nitrogen in someExpand
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Pain in end-stage renal disease: a frequent and neglected clinical problem.
Pain is a major health problem in end-stage renal disease (ESRD) affecting half of the dialysis patients; most of them experience a moderate to severe degree of pain. Nevertheless, the impact ofExpand
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Uremic autonomic neuropathy studied by spectral analysis of heart rate.
BACKGROUND There is good evidence that power spectral analysis (PSA) of heart rate variability may provide an insight into the understanding of autonomic disorders. METHODS We investigated 30Expand
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L-carnitine infusions may suppress serum C-reactive protein and improve nutritional status in maintenance hemodialysis patients.
Scattered reports indicate that L-carnitine may suppress proinflammatory cytokines in sick individuals without renal disease and may improve protein synthesis or nitrogen balance either in patientsExpand
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Renal alterations during exercise.
Proteinuria and hematuria are common during exercise. Proteinuria is usually due to glomerular or tubular changes or to an excessive production of protein as in myeloma. Certain clinical conditionsExpand
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Involvement of Interleukin-18 in Patients on Maintenance Haemodialysis
Maintenance dialysis induces a clinical state of immunodeficiency. The pathway of circulating T cells from haemodialyzed patients is changed and characterized by an increase of Th1 cells. TheExpand
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Impact of parathyroidectomy on cardiovascular outcomes and survival in chronic hemodialysis patients with secondary hyperparathyroidism. A retrospective study of 50 cases prior to the calcimimetics
BackgroundIn chronic hemodialysis patients with secondary hyperparathyroidism, pathological modifications of bone and mineral metabolism increase the risk of cardiovascular morbidity and mortality.Expand
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Carnitine-mediated improved response to erythropoietin involves induction of haem oxygenase-1: studies in humans and in an animal model.
BACKGROUND Carnitine improves erythropoetin (EPO) response and anaemia in haemodialysis patients (HD); however, the mechanism(s) responsible remain unidentified. We have reported that carnitineExpand
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