Carboplatin

Known as: CBDCA, cis-diammine(1,1-cyclobutanedicarboxylato) platinum(II), (SP-4-2)-diammine[1,1-cyclobutanedicarboxylato(2--)-O,O']platinum 
A second-generation platinum compound with a broad spectrum of antineoplastic properties. Carboplatin contains a platinum atom complexed with two… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND Activating mutations in EGFR are important markers of response to tyrosine kinase inhibitor (TKI) therapy in non-small… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Previous, uncontrolled studies have suggested that first-line treatment with gefitinib would be efficacious in… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Bevacizumab, a monoclonal antibody against vascular endothelial growth factor, has been shown to benefit patients with… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Erlotinib is a potent reversible HER1/epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor with single-agent… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE To investigate the efficacy and safety of bevacizumab plus carboplatin and paclitaxel in patients with advanced or… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE Preclinical studies indicate that gefitinib (Iressa, ZD1839; AstraZeneca, Wilmington, DE), an orally active epidermal… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE In randomized trials the combination of cisplatin and paclitaxel was superior to cisplatin and cyclophosphamide in… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND We conducted a randomized study to determine whether any of three chemotherapy regimens was superior to cisplatin and… (More)
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Highly Cited
1989
Highly Cited
1989
A dosage formula has been derived from a retrospective analysis of carboplatin pharmacokinetics in 18 patients with pretreatment… (More)
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