The Discovery and Development of Cisplatin

  title={The Discovery and Development of Cisplatin},
  author={R. Alderden and M. Hall and T. Hambley},
  journal={Journal of Chemical Education},
  • R. Alderden, M. Hall, T. Hambley
  • Published 2006
  • Chemistry
  • Journal of Chemical Education
  • Cisplatin is currently one of the most widely used anticancer drugs in the world. The unlikely events surrounding the discovery of its anticancer activity, subsequent introduction into the clinic, and the continuing research into platinum compounds is the subject of this review. Cisplatin and related platinum compounds remain the focus of extensive research. Reliable methods for the synthesis of such compounds have been developed and it has been established that they exert their anticancer… CONTINUE READING
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