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Cisplatin

Known as: Cisplatina, Cysplatyna, Cis-platinum II Diamine Dichloride 
An alkylating-like inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged… 
National Institutes of Health

Related topics

Related topics

49 relations

Broader (1)

Antineoplastic Agents
AstrocytomaCVACE protocolCVB protocolCisplatin 1 MG/ML Injectable Solution

Narrower (21)

BriplatinCE-AVN protocolCISCA protocolCOMPE protocol

Papers overview

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Highly Cited
1999
Highly Cited
1999
Metal String Complexes: Synthesis and Crystal Structure of [Ni4(μ4-phdpda)4] and [Ni7(μ7-teptra)4Cl2] (H2phdpda = N-Phenyldipyridyldiamine and H3teptra = Tetrapyridyltriamine)
In previous reports, the extension of dinuclear metal complexes10-12 to metal string complexes supported by oligoRpyridylamino… 
Highly Cited
1986
Highly Cited
1986
Purification of a functional receptor for calcium-channel blockers from rabbit skeletal-muscle microsomes.
The dihydropyridine receptor was purified from rabbit skeletal muscle microsomes in the presence of [3H]nitrendipine plus… 
Highly Cited
1982
Highly Cited
1982
Defective removal of DNA cross-links in a repair-deficient mutant of Chinese hamster cells.
To further understand the relationships between DNA damage, DNA repair, and cellular end points such as survival and mutation… 
Highly Cited
1980
Highly Cited
1980
Chemical structure and biodegradability of halogenated aromatic compounds. Halogenated muconic acids as intermediates.
Substituted muconic acids were prepared from the corresponding catechols by pyrocatechase II from Pseudomonas sp. B13. The… 
Highly Cited
1979
Highly Cited
1979
Binding of cis- and trans-dichlorodiammineplatinum(II) to DNA: evidence for unwinding and shortening of the double helix.
The antitumor drug cis-dichlorodiammineplatinum(II) (cis-DDP) and the inactive trans isomer bind and produce cooperative changes… 
Highly Cited
1979
Highly Cited
1979
Rationale for development of platinum analogs.
There is a great need for clinical trial of new second-generation platinum coordination compounds that might demonstrate greater… 
Highly Cited
1978
Highly Cited
1978
Kinetics of formation and disappearance of a DNA cross-linking effect in mouse leukemia L1210 cells treated with cis- and trans-diamminedichloroplatinum(II).
cis- and trans-diamminedichloroplatinum(II) (PDD) produced a DNA cross-linking effect in mouse leukemia L1210 cells, which was… 
Highly Cited
1977
Highly Cited
1977
Lack of cross-resistance between certain platinum coordination compounds in mouse leukemia.
Two congeners of cis-platinum diamminodichloride, 1,2-diamminocyclohexylplatinum malonate (NSC 224964) and 1,2… 
Highly Cited
1975
Highly Cited
1975
A 13C-NMR. Study of cis-trans isomeric vitamins A, carotenoids and related compounds.
The 1H-decoupled 13C-NMR. spectra of 35 all-trans, 17 mono-cis vitamin A compounds (acetates, alcohols, aldehydes, acids and… 
Review
1972
Review
1972
Mechanism of thermal decomposition of dibutylbis(triphenylphosphine)platinum(II)
The thermal decomposition of di-n-butylbis(triphenylphosphine)platinum(Il) (l) in methylene chloride to n-butane, l-butene, and a…