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Cisplatin

Known as: Cisplatina, Cysplatyna, Cis-platinum II Diamine Dichloride 
An alkylating-like inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged… 
National Institutes of Health

Related topics

Related topics

49 relations

Broader (1)

Antineoplastic Agents
AstrocytomaCVACE protocolCVB protocolCisplatin 1 MG/ML Injectable Solution

Narrower (21)

BriplatinCE-AVN protocolCISCA protocolCOMPE protocol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Arene cis-dihydrodiol formation: from biology to application.
The range of available arene dihydroxylating dioxygenase enzymes, their structure and mechanism, and recent examples of the… 
Highly Cited
2003
Highly Cited
2003
Intramolecular reactions of alkynes with furans and electron rich arenes catalyzed by PtCl2: the role of platinum carbenes as intermediates.
5-(2-Furyl)-1-alkynes react, with PtCl(2) as catalyst, to give phenols. On the basis of DFT calculations, a cyclopropyl… 
Review
2000
Review
2000
Three-dimensional intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: the University of California-San Francisco experience.
Highly Cited
1996
Highly Cited
1996
Detection of DNA‐crosslinking agents with the alkaline comet assay
The single cell gel electrophoresis, or comet assay, under alkaline conditions is a sensitive, simple and rapid method for the… 
Highly Cited
1989
Highly Cited
1989
A new methodology for the optimal design and production schedule of multipurpose batch plants
Presentation d'une procedure algorithmique determinant simultanement le programme optimal de production et les tailles des… 
Highly Cited
1981
Highly Cited
1981
cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils.
Highly Cited
1979
Highly Cited
1979
Binding of cis- and trans-dichlorodiammineplatinum(II) to DNA: evidence for unwinding and shortening of the double helix.
The antitumor drug cis-dichlorodiammineplatinum(II) (cis-DDP) and the inactive trans isomer bind and produce cooperative changes… 
Highly Cited
1977
Highly Cited
1977
Formation of singlet oxygen by the myeloperoxidase-mediated antimicrobial system.
Highly Cited
1977
Highly Cited
1977
Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas
Single agents and combinations of agents were tested for antitumor activity against four transplantable colon tumors in mice. The… 
Highly Cited
1972
Highly Cited
1972
Cross-linking of Complementary Strands of DNA in Mammalian Cells by Antitumour Platinum Compounds
Cis platinum (II) diammino-dichloride, cis Pt(II)(NH3)2Cl2 (A), is very effective against sarcoma 180 and leukaemia L 1210 in… 
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