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Cisplatin

Known as: Cisplatina, Cysplatyna, Cis-platinum II Diamine Dichloride 
An alkylating-like inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged… 
National Institutes of Health

Related topics

Related topics

49 relations

Broader (1)

Antineoplastic Agents
AstrocytomaCVACE protocolCVB protocolCisplatin 1 MG/ML Injectable Solution

Narrower (21)

BriplatinCE-AVN protocolCISCA protocolCOMPE protocol

Papers overview

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Review
2000
Review
2000
Three-dimensional intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: the University of California-San Francisco experience.
Highly Cited
1996
Highly Cited
1996
Detection of DNA‐crosslinking agents with the alkaline comet assay
The single cell gel electrophoresis, or comet assay, under alkaline conditions is a sensitive, simple and rapid method for the… 
Highly Cited
1989
Highly Cited
1989
A new methodology for the optimal design and production schedule of multipurpose batch plants
Presentation d'une procedure algorithmique determinant simultanement le programme optimal de production et les tailles des… 
Highly Cited
1988
Highly Cited
1988
Enhancement of the antiproliferative effect of cis‐diamminedichloroplatinum(II) and nitrogen mustard by inhibitors of protein kinase C
Quercetin (3, 3′, 4′, 5, 7‐pentahydroxyflavone) has been shown to inhibit a variety of enzymes including the calcium‐ and… 
Highly Cited
1985
Highly Cited
1985
The asymmetric synthesis of β-lactam antibiotics - I. application of chiral oxazolidones in the staudinger reaction.
Highly Cited
1981
Highly Cited
1981
cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils.
Highly Cited
1979
Highly Cited
1979
Binding of cis- and trans-dichlorodiammineplatinum(II) to DNA: evidence for unwinding and shortening of the double helix.
The antitumor drug cis-dichlorodiammineplatinum(II) (cis-DDP) and the inactive trans isomer bind and produce cooperative changes… 
Highly Cited
1978
Highly Cited
1978
Platinum complexes as radiosensitizers of hypoxic mammalian cells.
Cis-dichlorodiammineplatinum (II), or cis-PDD, has recently been shown to be a potent radiosensitizer of bacteria, particularly… 
Highly Cited
1977
Highly Cited
1977
Formation of singlet oxygen by the myeloperoxidase-mediated antimicrobial system.
Highly Cited
1977
Highly Cited
1977
Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas
Single agents and combinations of agents were tested for antitumor activity against four transplantable colon tumors in mice. The… 
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