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Carbonyl Reductase [NADPH] 3
Known as:
Carbonyl Reductase 3
, NADPH-Dependent Carbonyl Reductase 3
, EC 1.1.1.184
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Carbonyl reductase [NADPH] 3 (277 aa, ~31 kDa) is encoded by the human CBR3 gene. This protein plays a role in the reduction of metabolically active…
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National Institutes of Health
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Related topics
Related topics
7 relations
Arachidonic Acid Metabolism Pathway
CBR3 gene
Cytoplasmic matrix
Enzyme Gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Synthesis of 8-hydroxy-2-iminochromene derivatives as selective and potent inhibitors of human carbonyl reductase 1.
D-M Hu
,
Namiki Miyagi
,
+12 authors
S. Endo
Organic and biomolecular chemistry
2015
Corpus ID: 6286953
Human carbonyl reductase 1 (CBR1), a member of the short-chain dehydrogenase/reductase superfamily, reduces anthracycline…
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2014
2014
The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man.
Petra Malátková
,
L. Havlíková
,
V. Wsól
Chemico-Biological Interactions
2014
Corpus ID: 21419754
2012
2012
A conserved antioxidant response element (ARE) in the promoter of human carbonyl reductase 3 (CBR3) mediates induction by the master redox switch Nrf2.
Q. Cheng
,
J. Kalabus
,
Jianping Zhang
,
J. Blanco
Biochemical Pharmacology
2012
Corpus ID: 25603676
Review
2010
Review
2010
Human carbonyl reductases.
Petra Malátková
,
E. Maser
,
V. Wsól
Current drug metabolism
2010
Corpus ID: 23946736
Enzymatic carbonyl reduction means the formation of a hydroxy function out of a ketone or aldehyde moiety and applies for the…
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2009
2009
Identification of the Promoter of Human Carbonyl Reductase 3 (CBR3) and Impact of Common Promoter Polymorphisms on Hepatic CBR3 mRNA Expression
Jianping Zhang
,
J. Blanco
Pharmaceutical Research
2009
Corpus ID: 28118885
PurposeRecent studies suggest that polymorphisms in human carbonyl reductase 3 (CBR3) influence the pharmacodynamics of…
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2006
2006
Hyperconjugation and the increasing bulk of OCOCX3 substituents in trans-1,4-disubstituted cyclohexanes destabilize the diequatorial conformer.
E. Kleinpeter
,
Nadja Rolla
,
A. Koch
,
F. Taddei
Journal of Organic Chemistry
2006
Corpus ID: 40769255
The trans diesters of 1,4-cyclohexanediol with a number of acetic acid analogues, CX3COOH, of varying steric hindrance and…
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1998
1998
Mapping of a novel human carbonyl reductase, CBR3, and ribosomal pseudogenes to human chromosome 21q22.2.
K. Watanabe
,
C. Sugawara
,
+7 authors
T. Nomura
Genomics
1998
Corpus ID: 41557031
To find the genes contributing to Down syndrome, we constructed a 4-Mb sequence-ready map spanning chromosome 21q22.2 with…
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1997
1997
Carbonyl reduction of daunorubicin in rabbit liver and heart.
D. Pröpper
,
E. Maser
Acta Pharmacologica et Toxicologica
1997
Corpus ID: 2264734
A major problem of anthracycline anticancer treatment are the cardiotoxic side effects associated with drug therapy. Increased…
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1994
1994
Expression, crystallization and preliminary crystallographic analysis of human carbonyl reductase.
K. Bohren
,
B. Wermuth
,
David H. T. Harrison
,
Dagmar Ringe
,
G. Petsko
,
K. Gabbay
Journal of Molecular Biology
1994
Corpus ID: 1830734
The cDNA of human placental carbonyl reductase (EC 1.1.1.184), a member of the short-chain dehydrogenase family of enzymes, was…
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1987
1987
Inactivation of carbonyl reductase from human brain by phenylglyoxal and 2,3-butanedione: a comparison with aldehyde reductase and aldose reductase.
K. Bohren
,
J. von Wartburg
,
B. Wermuth
Biochimica et Biophysica Acta
1987
Corpus ID: 24672843
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