Skip to search formSkip to main contentSkip to account menu

Carbonyl Reductase [NADPH] 3

Known as: Carbonyl Reductase 3, NADPH-Dependent Carbonyl Reductase 3, EC 1.1.1.184 
Carbonyl reductase [NADPH] 3 (277 aa, ~31 kDa) is encoded by the human CBR3 gene. This protein plays a role in the reduction of metabolically active… 
National Institutes of Health

Related topics

Related topics

7 relations
Arachidonic Acid Metabolism PathwayCBR3 geneCytoplasmic matrixEnzyme Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Synthesis of 8-hydroxy-2-iminochromene derivatives as selective and potent inhibitors of human carbonyl reductase 1.
Human carbonyl reductase 1 (CBR1), a member of the short-chain dehydrogenase/reductase superfamily, reduces anthracycline… 
2014
2014
The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man.
2012
2012
A conserved antioxidant response element (ARE) in the promoter of human carbonyl reductase 3 (CBR3) mediates induction by the master redox switch Nrf2.
Review
2010
Review
2010
Human carbonyl reductases.
Enzymatic carbonyl reduction means the formation of a hydroxy function out of a ketone or aldehyde moiety and applies for the… 
2009
2009
Identification of the Promoter of Human Carbonyl Reductase 3 (CBR3) and Impact of Common Promoter Polymorphisms on Hepatic CBR3 mRNA Expression
PurposeRecent studies suggest that polymorphisms in human carbonyl reductase 3 (CBR3) influence the pharmacodynamics of… 
2006
2006
Hyperconjugation and the increasing bulk of OCOCX3 substituents in trans-1,4-disubstituted cyclohexanes destabilize the diequatorial conformer.
The trans diesters of 1,4-cyclohexanediol with a number of acetic acid analogues, CX3COOH, of varying steric hindrance and… 
1998
1998
Mapping of a novel human carbonyl reductase, CBR3, and ribosomal pseudogenes to human chromosome 21q22.2.
To find the genes contributing to Down syndrome, we constructed a 4-Mb sequence-ready map spanning chromosome 21q22.2 with… 
1997
1997
Carbonyl reduction of daunorubicin in rabbit liver and heart.
A major problem of anthracycline anticancer treatment are the cardiotoxic side effects associated with drug therapy. Increased… 
1994
1994
Expression, crystallization and preliminary crystallographic analysis of human carbonyl reductase.
The cDNA of human placental carbonyl reductase (EC 1.1.1.184), a member of the short-chain dehydrogenase family of enzymes, was… 
1987
1987
Inactivation of carbonyl reductase from human brain by phenylglyoxal and 2,3-butanedione: a comparison with aldehyde reductase and aldose reductase.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)