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Cancer/Testis Antigen 2
Known as:
LAGE-1
, Autoimmunogenic Cancer/Testis Antigen NY-ESO-2
, CT6.2
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Cancer/testis antigen 2 (210 aa, ~21 kDa) is encoded by the human CTAG2 gene. This protein may play a role in tumorigenesis of several tissues.
National Institutes of Health
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Related topics
Related topics
4 relations
CTAG2 gene
Cancer Promoting Genes
Metastasis Induction
Neoplastic Cell Transformation
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Expression of cancer–testis antigens in esophageal cancer and their progress in immunotherapy
Yujie Zhang
,
Yuxin Zhang
,
Li Zhang
Journal of Cancer Research and Clinical Oncology
2019
Corpus ID: 58014895
PurposeEsophageal cancer is a common disease in China with low survival rate due to no obvious early symptoms and lack of…
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2012
2012
Pattern of cancer/testis antigen expression in lung cancer patients
Yeongcheon Kim
,
Hae-Rim Park
,
+4 authors
Sang-Yull Lee
International Journal of Molecular Medicine
2012
Corpus ID: 2864580
Cancer/testis (CT) antigens represent promising targets for immunotherapy. We investigated the composite expression of 13 CT…
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2011
2011
Evaluation of LAGE-1 and NY-ESO-1 expression in multiple myeloma patients to explore possible benefits of their homology for immunotherapy.
Fabrício de Carvalho
,
A. Vettore
,
+5 authors
G. Colleoni
Cancer Immunity
2011
Corpus ID: 22168778
Due to the high homology between the LAGE-1 and NY-ESO-1 proteins, we hypothesized that an anti-NY-ESO-1 vaccine might elicit…
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Highly Cited
2007
Highly Cited
2007
Prognostic impact of cancer/testis antigen expression in advanced stage multiple myeloma patients.
V. C. Andrade
,
A. Vettore
,
+8 authors
G. Colleoni
Cancer Immunity
2007
Corpus ID: 28179611
This study aims to analyze the expression of 14 cancer/testis (CT) antigens in multiple myeloma (MM) to identify possible…
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Highly Cited
2004
Highly Cited
2004
Serological cloning of cancer/testis antigens expressed in prostate cancer using cDNA phage surface display
A. Fosså
,
L. Alsøe
,
R. Crameri
,
S. Funderud
,
G. Gaudernack
,
E. Smeland
Cancer Immunology and Immunotherapy
2004
Corpus ID: 22355174
Serological cloning of tumor-associated antigens (TAAs) using patient autoantibodies and tumor cDNA expression libraries (SEREX…
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Highly Cited
2004
Highly Cited
2004
Immunohistochemical and Molecular Analysis of Human Melanomas for Expression of the Human Cancer-Testis Antigens NY-ESO-1 and LAGE-1
H. Vaughan
,
S. Svobodová
,
+10 authors
J. Cebon
Clinical Cancer Research
2004
Corpus ID: 6108015
Purpose: NY-ESO-1 and LAGE-1 are homologous cancer-testis antigens, which are expressed in many different cancers. It is…
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Highly Cited
2003
Highly Cited
2003
NY-ESO-1 and LAGE-1 cancer-testis antigens are potential targets for immunotherapy in epithelial ovarian cancer.
K. Odunsi
,
A. Jungbluth
,
+15 authors
L. Old
Cancer Research
2003
Corpus ID: 6655901
Cancer-testis (CT) antigens are expressed in a variety of cancers, but not in normal adult tissues, except for germ cells of the…
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Review
2002
Review
2002
Towards Defining Specific Antigens for Cutaneous Lymphomas
Stefan B. Eichmüller
Oncology Research and Treatment
2002
Corpus ID: 10892057
Cutaneous lymphomas (CLs) are a heterogeneous group of malignancies of T-cell (cutaneous T-cell lymphoma, CTCL) or B-cell…
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Highly Cited
2001
Highly Cited
2001
Expression of multiple cancer-testis antigen genes in gastrointestinal and breast carcinomas
Kohjiro Mashino
,
N. Sadanaga
,
+5 authors
M. Mori
British Journal of Cancer
2001
Corpus ID: 7014580
Cancer-testis antigens (CTAs) such as MAGE are selectively expressed in various types of human neoplasms but not in normal…
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Highly Cited
1998
Highly Cited
1998
Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library.
Yao-Tseng Chen
,
A. Gure
,
+4 authors
Lloyd J. Old
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 12531568
Cancer/testis (CT) antigens-immunogenic protein antigens that are expressed in testis and a proportion of diverse human cancer…
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