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Calusterone

Known as: 7-beta,17-Dimethyltestosterone, Androst-4-en-3-one, 17.beta.-hydroxy-7.beta.,17-dimethyl- (8CI), Androst-4-en-3-one, 17-hydroxy-7,17-dimethyl-, (7.beta., 17.beta.)- (9CI) 
A 17-alkylated orally active androgenic steroid. Calusterone may alter the metabolism of estradiol and reduce estrogen production. (NCI04)
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Methyltestosterone
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
Micellar electrokinetic capillary chromatographic separation of steroids in urine by trioctylphosphine oxide and cationic surfactant.
1991
1991
[Value of hemodilution therapy in pregnancy].
The ability to produce a large increase in plasma volume is one of the hallmarks of a successful pregnancy. Data from Garn et al… 
1983
1983
Characterization of microsomal epoxide hydrolase in hyperplastic liver nodules of rats.
Microsomal epoxide hydrolase, a major antigenic marker of putative preneoplastic hepatocytes was studied in hyperplastic liver… 
1981
1981
The effects of calusterone on hemopoiesis in mice after busulfan-induced suppression of hemopoietic stem cells.
Studies were undertaken in mice to determine the effect of calusterone (a weakly androgenic steroid) on hemopoiesis. Animals were… 
1979
1979
Comparative trial of low‐dose adriamycin plus cyclophosphamide with or without additive hormonal therapy in advanced breast cancer
We treated 56 women with advanced metastatic breast cancer who had not received prior chemotherapy in a comparative trial of… 
1976
1976
Effect of 7β,17α-Dimethyltestosterone (Calusterone) on Cortisol Metabolism in Women with Advanced Breast Cancer
Abstract It was demonstrated that oral administration of 7β,17α-dimethyltestosterone (Calusterone) reversibly alters cortisol… 
1973
1973
Calusterone (7β,17α-DimethyItestosterone) as Primary and Secondary Therapy of Advanced Breast Cancer
The antitumor efficacy of calusterone, 200 mg/day by mouth, against objectively progressing advanced breast cancer was evaluated… 
Highly Cited
1973
Highly Cited
1973
Androgenic therapy for advanced breast cancer in women. A report of the cooperative breast cancer group.
A randomized clinical trial of calusterone and testolactone according to the protocol of the Cooperative Breast Cancer Group… 
1972
1972
Calusterone in the therapy for advanced breast cancer.
Dr. Theodore J. Hahn, Fellow in Endocrinology, the Jewish Hospital of St. Louis, and Assistant in Medicine, Washington University… 
1970
1970
Antitumor Efficacy of 7β, 17α-Dimethyltestosterone (Calusterone) in Advanced Female Breast Cancer
Twenty-two women with far advanced, hormone-refractory breast cancer were treated with 7β,17α dimethyltestosterone (calusterone… 
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