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Calcium-Activated Potassium Channel Subunit Alpha-1

Known as: BKCA Alpha, MaxiK, Slo-Alpha 
Calcium-activated potassium channel subunit alpha-1 (1236 aa, ~138 kDa) is encoded by the human KCNMA1 gene. This protein plays a role in calcium… 
National Institutes of Health

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18 relations
Apical Domain of the EpitheliumBlood coagulationCaveolaeCellular Membrane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Channel beta2-4 subunits fail to substitute for beta1 in sensitizing BK channels to lithocholate.
2008
2008
Potentiation of large-conductance calcium-activated potassium (BK(Ca)) channels by a specific isoform of protein kinase C.
2004
2004
Flow by a Ring of Negative Charges in the Outer Pore of BK Ca Channels . Part I : Aspartate 292 modulates K Conduction by External Surface Charge Effect
The pore region of the majority of K channels contains the highly conserved GYGD sequence, known as the K channel signature… 
2003
2003
The Cytoplasmic Tail of Large Conductance, Voltage- and Ca2+-activated K+ (MaxiK) Channel Is Necessary for Its Cell Surface Expression*
The large conductance, voltage- and Ca2+-activated K+ channel (MaxiK) is expressed in several renal segments and functions in… 
2002
2002
Prostaglandin E2 Induces Interaction Between hSlo Potassium Channel and Syk Tyrosine Kinase in Osteosarcoma Cells
Prostaglandins (PGs) are important mediators of bone response to growth factors, hormones, inflammation, or mechanical strains… 
2002
2002
Slo1 Tail Domains, but Not the Ca2+ Bowl, Are Required for the β1 Subunit to Increase the Apparent Ca2+ Sensitivity of BK Channels
Functional large-conductance Ca2+- and voltage-activated K+ (BK) channels can be assembled from four α subunits (Slo1) alone, or… 
2002
2002
Reciprocal Modulation between the α and β4 Subunits of hSlo Calcium-dependent Potassium Channels*
Large conductance Ca2+-dependent potassium (KCaor maxi K) channels are composed of a pore-forming α subunit and an auxiliary… 
Highly Cited
1998
Highly Cited
1998
Glucocorticoid Regulation of Calcium-activated Potassium Channels Mediated by Serine/Threonine Protein Phosphatase*
Adrenal glucocorticoids exert powerful effects on cellular excitability in neuroendocrine cells and neurons, although the… 
Highly Cited
1998
Highly Cited
1998
dSLo Interacting Protein 1, a Novel Protein That Interacts with Large-Conductance Calcium-Activated Potassium Channels
Large-conductance calcium-activated potassium channels (BK channels) are activated by depolarized membrane potential and elevated… 
1998
1998
Regulation of stably expressed and native BK channels from human myometrium by cGMP- and cAMP-dependent protein kinase
Abstract The cloned BK channel α subunit from human myometrium was stably expressed in Chinese hamster ovary cells, either alone… 
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