Caffeic Acid Phenethyl Ester

Known as: phenethyl caffeate, 2-Phenylethyl 3-(3,4-dihydroxyphenyl)-2-propenoate, CAPEEE 
The phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis, with antineoplastic, cytoprotective and… (More)
National Institutes of Health

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Broader (2)

Caffeic AcidsPhenylethyl Alcohol
analogs & derivativesphenyl caffeate

Papers overview

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Highly Cited
2005
Highly Cited
2005
Caffeic acid phenethyl ester protects kidneys against carbon tetrachloride toxicity in rats.
Caffeic acid phenethyl ester (CAPE), an active component of propolis produced by honeybees, exhibits antioxidant and anti… (More)
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2004
2004
Caffeic acid phenethyl ester prevents neonatal hypoxic-ischaemic brain injury.
Neonatal hypoxic-ischaemic (HI) brain injury resulting in encephalopathy is a leading cause of morbidity and mortality with no… (More)
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Highly Cited
2002
Highly Cited
2002
Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers.
Heme oxygenase-1 (HO-1) is a redox-sensitive inducible protein that provides efficient cytoprotection against oxidative stress… (More)
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Highly Cited
2002
Highly Cited
2002
Antioxidant activity of propolis: role of caffeic acid phenethyl ester and galangin.
Propolis, a natural product produced by the honeybee, has been used for thousands of years in folk medicine for several purposes… (More)
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1999
1999
Caffeic acid phenethyl ester prevents intestinal reperfusion injury in rats.
BACKGROUND/PURPOSE Ischemia-reperfusion injury is encountered frequently in conditions that diminish intestinal blood flow… (More)
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Highly Cited
1999
Highly Cited
1999
The effects of caffeic acid phenethyl ester (CAPE) on spinal cord ischemia/reperfusion injury in rabbits.
OBJECTIVE Oxygen-derived free radicals have been implicated in the pathogenesis of spinal cord neuronal injury after both trauma… (More)
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Highly Cited
1999
Highly Cited
1999
Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation.
We investigated the mechanisms by which caffeic acid phenethyl ester (CAPE), a phenolic antioxidant, inhibited the stimulation of… (More)
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Highly Cited
1996
Highly Cited
1996
Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.
Caffeic acid phenethyl ester (CAPE), an active component of propolis from honeybee hives, is known to have antimitogenic… (More)
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Highly Cited
1993
Highly Cited
1993
Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties.
Caffeic acid phenethyl ester, an active component of propolis extract, inhibits 5-lipoxygenase in the micromolar concentration… (More)
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Highly Cited
1988
Highly Cited
1988
Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis
The honeybee hive product, propolis, is a folk medicine employed for treating various ailments. Many important pharmaceutical… (More)
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