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- Publications
- Influence
The Atlantic salmon genome provides insights into rediploidization
- S. Lien, B. Koop, +42 authors W. Davidson
- Biology, Medicine
- Nature
- 12 May 2016
The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique opportunities to learn about… Expand
A dense SNP-based linkage map for Atlantic salmon (Salmo salar) reveals extended chromosome homeologies and striking differences in sex-specific recombination patterns
- S. Lien, L. Gidskehaug, +5 authors M. Kent
- Biology, Medicine
- BMC Genomics
- 19 December 2011
BackgroundThe Atlantic salmon genome is in the process of returning to a diploid state after undergoing a whole genome duplication (WGD) event between 25 and100 million years ago. Existing data on… Expand
Comparative Genomics Identifies a Flagellar and Basal Body Proteome that Includes the BBS5 Human Disease Gene
- J. Li, J. Gerdes, +18 authors S. Dutcher
- Biology, Medicine
- Cell
- 14 May 2004
Cilia and flagella are microtubule-based structures nucleated by modified centrioles termed basal bodies. These biochemically complex organelles have more than 250 and 150 polypeptides, respectively.… Expand
Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport.
- O. Blacque, M. Reardon, +15 authors M. Leroux
- Biology, Medicine
- Genes & development
- 1 July 2004
Bardet-Biedl syndrome (BBS) is a genetically heterogeneous developmental disorder whose molecular basis is largely unknown. Here, we show that mutations in the Caenorhabditis elegans bbs-7 and bbs-8… Expand
Sequencing the genome of the Atlantic salmon (Salmo salar)
- W. Davidson, B. Koop, +6 authors S. Omholt
- Biology, Medicine
- Genome Biology
- 30 September 2010
The International Collaboration to Sequence the Atlantic Salmon Genome (ICSASG) will produce a genome sequence that identifies and physically maps all genes in the Atlantic salmon genome and acts as… Expand
Clinical and genetic epidemiology of Bardet–Biedl syndrome in Newfoundland: A 22‐year prospective, population‐based, cohort study
- S. J. Moore, J. Green, +12 authors P. Parfrey
- Medicine
- American journal of medical genetics. Part A
- 1 February 2005
Bardet–Biedl syndrome (BBS) and Laurence–Moon syndrome (LMS) have a similar phenotype, which includes retinal dystrophy, obesity, and hypogenitalism. They are differentiated by the presence of… Expand
A salmonid EST genomic study: genes, duplications, phylogeny and microarrays
- B. Koop, K. R. von Schalburg, +12 authors W. Davidson
- Biology, Medicine
- BMC Genomics
- 17 November 2008
BackgroundSalmonids are of interest because of their relatively recent genome duplication, and their extensive use in wild fisheries and aquaculture. A comprehensive gene list and a comparison of… Expand
Triallelic Inheritance in Bardet-Biedl Syndrome, a Mendelian Recessive Disorder
- N. Katsanis, S. J. Ansley, +7 authors J. Lupski
- Biology, Medicine
- Science
- 21 September 2001
Bardet-Biedl syndrome (BBS) is a genetically heterogeneous disorder characterized by multiple clinical features that include pigmentary retinal dystrophy, polydactyly, obesity, developmental delay,… Expand
Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome
RAB, ADP-ribosylation factors (ARFs) and ARF-like (ARL) proteins belong to the Ras superfamily of small GTP-binding proteins and are essential for various membrane-associated intracellular… Expand
Mutations in MKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome
- N. Katsanis, P. Beales, +6 authors J. Lupski
- Biology, Medicine
- Nature Genetics
- 1 September 2000
Bardet-Biedl syndrome (BBS) is an autosomal recessive disorder predominantly characterized by obesity, retinal dystrophy, polydactyly, learning difficulties, hypogenitalism and renal malformations,… Expand
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