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CYSLTR1 gene

Known as: CysLT(1), CYSLT1, CYSLTR1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Leukotriene E4–induced pulmonary inflammation is mediated by the P2Y12 receptor
Of the potent lipid inflammatory mediators comprising the cysteinyl leukotrienes (LTs; LTC4, LTD4, and LTE4), only LTE4 is stable… Expand
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Highly Cited
2007
Highly Cited
2007
Overexpression of cysteinyl LT1 receptor in prostate cancer and CysLT1R antagonist inhibits prostate cancer cell growth through apoptosis.
The metabolism of arachidonic acid by either cyclooxygenase or lipoxygenase is believed to play an important role in… Expand
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Highly Cited
2007
Highly Cited
2007
Cysteinyl Leukotrienes Are Autocrine and Paracrine Regulators of Fibrocyte Function1
Pulmonary fibrosis is characterized by the accumulation of fibroblasts and myofibroblasts. These cells may accumulate from three… Expand
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Highly Cited
2006
Highly Cited
2006
Montelukast protects against renal ischemia/reperfusion injury in rats.
BACKGROUND Oxygen free radicals are important components involved in the pathophysiological processes observed during ischemia… Expand
Highly Cited
2004
Highly Cited
2004
Characterization of interleukin-4-stimulated nasal polyp fibroblasts.
Chronic hyperplastic eosinophilic sinusitis is an inflammatory disease that results in the accumulation of eosinophils… Expand
Highly Cited
2002
Highly Cited
2002
Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis.
BACKGROUND Patients with asthma who have aspirin sensitivity have greater cysteinyl leukotriene production and greater airway… Expand
Highly Cited
2001
Highly Cited
2001
Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells
The cysteinyl leukotrienes (cys-LTs) LTC4, LTD4, and LTE4 are a class of peptide-conjugated lipids formed from arachidonic acid… Expand
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Highly Cited
2001
Highly Cited
2001
Chemotaxis and transendothelial migration of CD34(+) hematopoietic progenitor cells induced by the inflammatory mediator leukotriene D4 are mediated by the 7-transmembrane receptor CysLT1.
Recent studies suggest that bone marrow (BM)-derived chemotactic mediators such as chemokines play key roles in hematopoietic… Expand
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Highly Cited
2001
Highly Cited
2001
Levels of cysteinyl leukotriene receptor mRNA in human peripheral leucocytes: significantly higher expression of cysteinyl leukotriene receptor 2 mRNA in eosinophils
Background Cysteinyl leukotrienes (CysLTs) have been implicated as important contributors in the pathophysiology of asthma and… Expand
Highly Cited
1999
Highly Cited
1999
Characterization of the human cysteinyl leukotriene CysLT1 receptor
The cysteinyl leukotrienes—leukotriene C4(LTC4), leukotriene D4(LTD4) and leukotriene E4(LTE 4)—are important mediators of human… Expand
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